Next Article in Journal
Next Article in Special Issue
Previous Article in Journal
Previous Article in Special Issue
Molecules 2011, 16(1), 609-623; doi:10.3390/molecules16010609
Article

Chemistry of the Enaminone of 1-Acetylnaphthalene under Microwave Irradiation Using Chitosan as a Green Catalyst

Received: 9 November 2010; in revised form: 4 January 2011 / Accepted: 6 January 2011 / Published: 17 January 2011
(This article belongs to the Special Issue Advances in Heterocyclic Chemistry)
Download PDF [158 KB, uploaded 18 June 2014]
Abstract: Enaminone 1 was reacted with hydrazonoyl halides 2a-d to yield 3,4-disubstituted pyrazoles 6a-d. Coupling with arenediazonium chlorides afforded the 2-(arylhydrazono)-3-(1-naphthalenyl)-3-oxopropionaldehydes 13a-c. Compounds 13 could be utilized for the synthesis of a variety of arylpyrazoles, arylazolopyrimidines, and pyridazinones via reaction with hydrazines, aminoazoles, and active methylene derivatives, respectively. A comparative study of aforementioned reactions was carried out with chitosan as a basic ecofriendly catalyst under conventional heating as well as under pressurized microwave irradiation conditions.
Keywords: chitosan; 1-acetylnaphthalene; microwave irradiation; enaminone; hydrazonoyl halides chitosan; 1-acetylnaphthalene; microwave irradiation; enaminone; hydrazonoyl halides
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Hassaneen, H.M.E. Chemistry of the Enaminone of 1-Acetylnaphthalene under Microwave Irradiation Using Chitosan as a Green Catalyst. Molecules 2011, 16, 609-623.

AMA Style

Hassaneen HME. Chemistry of the Enaminone of 1-Acetylnaphthalene under Microwave Irradiation Using Chitosan as a Green Catalyst. Molecules. 2011; 16(1):609-623.

Chicago/Turabian Style

Hassaneen, Huwaida M. E. 2011. "Chemistry of the Enaminone of 1-Acetylnaphthalene under Microwave Irradiation Using Chitosan as a Green Catalyst." Molecules 16, no. 1: 609-623.



Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert