Molecules 2010, 15(6), 4401-4407; doi:10.3390/molecules15064401
Communication

Preparation and Physicochemical Properties of the Complex of Naringenin with Hydroxypropyl-β-Cyclodextrin

Received: 5 May 2010; in revised form: 7 June 2010 / Accepted: 9 June 2010 / Published: 18 June 2010
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: In this study a complex of naringenin with hydroxypropyl-β-cyclodextrin (HP-β-CD) was prepared to improve the hydrophilicity of naringenin. The physicochemical properties of the complex were analyzed by ultraviolet-visible spectrometry (UV), infrared spectrometry (IR), X-ray diffractometry (XRD), differential scanning calorimetry (DSC). The result showed that naringenin had been molecularly dispersed in the HP-β-CD matrix, not forming a new compound and HPLC analysis showed that the solubility of naringenin in water was enhanced from 4.38 μg/mL to 1,272.31 μg/mL.
Keywords: naringenin; hydroxypropyl-β-cyclodextrin; complex; flavonoid
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MDPI and ACS Style

Wen, J.; Liu, B.; Yuan, E.; Ma, Y.; Zhu, Y. Preparation and Physicochemical Properties of the Complex of Naringenin with Hydroxypropyl-β-Cyclodextrin. Molecules 2010, 15, 4401-4407.

AMA Style

Wen J, Liu B, Yuan E, Ma Y, Zhu Y. Preparation and Physicochemical Properties of the Complex of Naringenin with Hydroxypropyl-β-Cyclodextrin. Molecules. 2010; 15(6):4401-4407.

Chicago/Turabian Style

Wen, Jiping; Liu, Benguo; Yuan, Erdong; Ma, Yuxiang; Zhu, Yongyi. 2010. "Preparation and Physicochemical Properties of the Complex of Naringenin with Hydroxypropyl-β-Cyclodextrin." Molecules 15, no. 6: 4401-4407.

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