Next Article in Journal
Synthesis of 2- and 7- Substituted C19 Steroids Having a 1,4,6-Triene or 1,4-Diene Structure and Their Cytotoxic Effects on T47D and MDA-MB231 Breast Cancer Cells
Previous Article in Journal
Lead Generation and Optimization Based on Protein-Ligand Complementarity
Article Menu

Article Versions

Export Article

Open AccessCommunication
Molecules 2010, 15(6), 4401-4407; doi:10.3390/molecules15064401

Preparation and Physicochemical Properties of the Complex of Naringenin with Hydroxypropyl-β-Cyclodextrin

College of Grain and Food, Henan University of Technology, Zhengzhou 450052, China
School of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China
College of Light Industry and Food Science, South China University of Technology, Guangzhou 510640, China
Author to whom correspondence should be addressed.
Received: 5 May 2010 / Revised: 7 June 2010 / Accepted: 9 June 2010 / Published: 18 June 2010
Download PDF [270 KB, uploaded 18 June 2014]


In this study a complex of naringenin with hydroxypropyl-β-cyclodextrin (HP-β-CD) was prepared to improve the hydrophilicity of naringenin. The physicochemical properties of the complex were analyzed by ultraviolet-visible spectrometry (UV), infrared spectrometry (IR), X-ray diffractometry (XRD), differential scanning calorimetry (DSC). The result showed that naringenin had been molecularly dispersed in the HP-β-CD matrix, not forming a new compound and HPLC analysis showed that the solubility of naringenin in water was enhanced from 4.38 μg/mL to 1,272.31 μg/mL.
Keywords: naringenin; hydroxypropyl-β-cyclodextrin; complex; flavonoid naringenin; hydroxypropyl-β-cyclodextrin; complex; flavonoid
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Wen, J.; Liu, B.; Yuan, E.; Ma, Y.; Zhu, Y. Preparation and Physicochemical Properties of the Complex of Naringenin with Hydroxypropyl-β-Cyclodextrin. Molecules 2010, 15, 4401-4407.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top