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Molecules 2010, 15(5), 3567-3577; doi:10.3390/molecules15053567
Article

Phenolic Extracts from Acacia mangium Bark and Their Antioxidant Activities

1,2,* , 1, 1,2, 1,2 and 1
Received: 31 March 2010; in revised form: 8 May 2010 / Accepted: 12 May 2010 / Published: 14 May 2010
(This article belongs to the Special Issue Phenolics and Polyphenolics)
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Abstract: Phenolic compounds are present at very high concentrations in the bark of Acacia mangium. These compounds are known to have strong antioxidant activity and thus different beneficial effects on human health. Phenolic compounds in bark of A. mangium were extracted and their antioxidant activities were investigated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging and ferric-reducing antioxidant power (FRAP) assays. A central composite design has been employed to optimize the experimental conditions for a high total phenolic content and antioxidant activity. The desirability function approach has been employed to simultaneously optimize the three responses: total phenols, antiradical activity and FRAP. An extraction time of 90 min, liquid-solid ratio of 5, and temperature of 50 °C was predicted for the optimum experimental conditions using the desirability function. A significant linear relationship between antioxidant potency, antiradical activity and the content of phenolic compounds of bark extracts was observed. The structures of condensed tannins isolated from A. mangium were characterized by MALDI-TOF MS analyses. Condensed tannin oligomers from A. mangium were shown to be heterogeneous mixtures consisting of procyanidin and prodelphinidin structural units with polymerization degrees up to 9.
Keywords: Acacia mangium; phenolic compounds; condensed tannins; antioxidant activities; central composite design Acacia mangium; phenolic compounds; condensed tannins; antioxidant activities; central composite design
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Zhang, L.; Chen, J.; Wang, Y.; Wu, D.; Xu, M. Phenolic Extracts from Acacia mangium Bark and Their Antioxidant Activities. Molecules 2010, 15, 3567-3577.

AMA Style

Zhang L, Chen J, Wang Y, Wu D, Xu M. Phenolic Extracts from Acacia mangium Bark and Their Antioxidant Activities. Molecules. 2010; 15(5):3567-3577.

Chicago/Turabian Style

Zhang, Liangliang; Chen, Jiahong; Wang, Yongmei; Wu, Dongmei; Xu, Man. 2010. "Phenolic Extracts from Acacia mangium Bark and Their Antioxidant Activities." Molecules 15, no. 5: 3567-3577.


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