Molecules 2010, 15(5), 3211-3227; doi:10.3390/molecules15053211
Article

Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide

School of Chemistry, Main Building, Cardiff University, Park Place, Cardiff, CF10 3AT, UK
* Author to whom correspondence should be addressed.
Received: 22 March 2010; Accepted: 20 April 2010 / Published: 30 April 2010
(This article belongs to the Special Issue Organic Iodine Chemistry)
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Abstract: Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N-iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regiocontrol.
Keywords: Bohlmann-Rahtz synthesis; cyclization reactions; heterocycles; Lewis acids; pyridines

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MDPI and ACS Style

Bagley, M.C.; Glover, C. Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide. Molecules 2010, 15, 3211-3227.

AMA Style

Bagley MC, Glover C. Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide. Molecules. 2010; 15(5):3211-3227.

Chicago/Turabian Style

Bagley, Mark C.; Glover, Christian. 2010. "Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide." Molecules 15, no. 5: 3211-3227.

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