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Molecules 2010, 15(5), 3211-3227; doi:10.3390/molecules15053211
Article

Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide

*  and
Received: 22 March 2010; Accepted: 20 April 2010 / Published: 30 April 2010
(This article belongs to the Special Issue Organic Iodine Chemistry)
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Abstract: Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N-iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regiocontrol.
Keywords: Bohlmann-Rahtz synthesis; cyclization reactions; heterocycles; Lewis acids; pyridines Bohlmann-Rahtz synthesis; cyclization reactions; heterocycles; Lewis acids; pyridines
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Bagley, M.C.; Glover, C. Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide. Molecules 2010, 15, 3211-3227.

AMA Style

Bagley MC, Glover C. Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide. Molecules. 2010; 15(5):3211-3227.

Chicago/Turabian Style

Bagley, Mark C.; Glover, Christian. 2010. "Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide." Molecules 15, no. 5: 3211-3227.


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