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Molecules 2010, 15(4), 2339-2346; doi:10.3390/molecules15042339
Article

(6,7-Dimethoxy-4-methylisoquinolinyl)-(4’-methoxyphenyl)-methanone, a New Benzylisoquinoline Alkaloid from Beilschmiedia brevipes

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1 Department of Chemistry, Faculty of Science and Technology, University Airlangga, Surabaya, Indonesia 2 Centre for Natural Products and Drug Discovery, Block D, Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia 3 Department of Chemistry, Faculty of Science and Mathematics, University of Syah Kuala, Banda Aceh, Indonesia 4 Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa, Tokyo 142-8501, Japan 5 Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles, CNRS, 1, Avenue de la Terrasse, 91198 Gif-sur-Yvette Cedex, France
* Author to whom correspondence should be addressed.
Received: 19 January 2010 / Revised: 8 February 2010 / Accepted: 1 March 2010 / Published: 31 March 2010
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Abstract

The leaves of Beilschmiedia brevipes provided a new benzylisoquinoline alkaloid: (6,7-dimethoxy-4-methylisoquinolinyl)-(4’-methoxyphenyl)-methanone (1) and O,O-dimethylannocherin A (2), a new natural compound which has been synthesized before. Complete 1H- and 13C-NMR data of both compounds were reported. The structures were established through various spectroscopic methods notably 1D- and 2D-NMR, UV, IR and HRESIMS.
Keywords: Beilschmiedia brevipes; benzylisoquinoline; lauraceae; NMR Beilschmiedia brevipes; benzylisoquinoline; lauraceae; NMR
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Pudjiastuti, P.; Mukhtar, M.R.; Hadi, A.H.A.; Saidi, N.; Morita, H.; Litaudon, M.; Awang, K. (6,7-Dimethoxy-4-methylisoquinolinyl)-(4’-methoxyphenyl)-methanone, a New Benzylisoquinoline Alkaloid from Beilschmiedia brevipes. Molecules 2010, 15, 2339-2346.

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