A New Flavone C-Glycoside from Clematis rehderiana

doi:10.3390/molecules15020672

This article is

freely available
re-usable

Molecules 2010, 15(2), 672-679; doi:10.3390/molecules15020672

Communication

A New Flavone C-Glycoside from Clematis rehderiana

Zhi-Zhi Du ¹ , Xian-Wen Yang ² , Hao Han ¹, Xiang-Hai Cai ¹ and Xiao-Dong Luo ¹^,*

¹ State Key Laboratory of Phytochemistry and Plant Resources of West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China ² Key Laboratory of Marine Bioresources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China

* Author to whom correspondence should be addressed.

Received: 24 December 2009; in revised form: 28 January 2010 / Accepted: 29 January 2010 / Published: 29 January 2010

Download PDF Full-Text [228 KB, uploaded 29 January 2010 14:00 CET]

Abstract: A new flavone C-glycoside, isovitexin 6″-O-E-p-coumarate (1) and two known flavonoid glycosides—quercetin 3-O-β-D-glucuronopyranoside (2) and isoorientin (3)—were isolated from an ethanol extract of aerial parts of Clematis rehderiana. Their structures were determined by spectroscopic methods. The antioxidant effects of the two flavone C-glycosides were evaluated by both the MTT and DPPH assays. Compound 1 showed potent activities against H₂O₂-induced impairment in PC12 cells within the concentration range tested, whereas compound 3 scavenged DPPH radical strongly, with an IC₅₀ value of 13.5 μM.

Keywords: Clematis rehderiana; flavonoide glycosides; antioxidant

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Du, Z.-Z.; Yang, X.-W.; Han, H.; Cai, X.-H.; Luo, X.-D. A New Flavone C-Glycoside from Clematis rehderiana. Molecules 2010, 15, 672-679.

AMA Style

Du Z.-Z., Yang X.-W., Han H., Cai X.-H., Luo X.-D. A New Flavone C-Glycoside from Clematis rehderiana. Molecules. 2010; 15(2):672-679.

Chicago/Turabian Style

Du, Zhi-Zhi; Yang, Xian-Wen; Han, Hao; Cai, Xiang-Hai; Luo, Xiao-Dong. 2010. "A New Flavone C-Glycoside from Clematis rehderiana." Molecules 15, no. 2: 672-679.

Molecules EISSN 1420-3049 Published by MDPI Publishing, Basel, Switzerland RSS E-Mail Table of Contents Alert