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Roy et al. On Two Novel Parameters for Validation of Predictive QSAR Models. Molecules, 2009, 14, 1660-1701
Molecules 2010, 15(2), 606-612; doi:10.3390/molecules15020606
Article

Caloxanthones O and P: Two New Prenylated Xanthones from Calophyllum inophyllum

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 and
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1 Key Laboratory of Tropical Crop Biotechnology, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, Hainan, China 2 International Joint Laboratory for Research and Development of Tropical Medicinal Plants, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China 3 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China
* Author to whom correspondence should be addressed.
Received: 30 November 2009 / Revised: 4 January 2010 / Accepted: 8 January 2010 / Published: 27 January 2010
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Abstract

Chemical investigation of the EtOH extract of the twigs of Calophyllum inophyllum collected in Hainan Province of China resulted in the isolation of two new prenylated xanthones, caloxanthone O (1) and caloxanthone P (2). Their structures were elucidated by a study of their physical and spectral data. Compound 1 exhibited cytotoxicity against human gastric cancer cell line (SGC-7901),with an IC50 value of 22.4 μg mL-1.
Keywords: Calophyllum inophyllum; caloxanthone O; caloxanthone P; cytotoxic activity; prenylated xanthones Calophyllum inophyllum; caloxanthone O; caloxanthone P; cytotoxic activity; prenylated xanthones
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Dai, H.-F.; Zeng, Y.-B.; Xiao, Q.; Han, Z.; Zhao, Y.-X.; Mei, W.-L. Caloxanthones O and P: Two New Prenylated Xanthones from Calophyllum inophyllum. Molecules 2010, 15, 606-612.

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