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Molecules 2010, 15(12), 9418-9426; doi:10.3390/molecules15129418
Article

Facile and Convenient Synthesis of New Thieno[2,3-b]-Thiophene Derivatives

1,* , 2,†
 and 1
1 Department of Chemistry, Faculty of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia 2 Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt Current Address: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Khalid University, Abha, Saudi Arabia
* Author to whom correspondence should be addressed.
Received: 12 October 2010 / Revised: 15 December 2010 / Accepted: 16 December 2010 / Published: 20 December 2010
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Abstract

A facile and convenient synthesis of bis(2-(1H-benzo[d]imidazol-2(3H)-ylidene)-3-oxopropanenitrile), bis((3-amino-5-(methylthio)-1H-pyrazol-4-yl)methanone) and bis(2-thioxo-1,2-dihydropyrimidine-5-carbonitrile) derivatives incorporating a thieno- [2,3-b]thiophene moiety via versatile, readily accessible diethyl 3,4-dimethylthieno-[2,3-b]thiophene-2,5-dicarboxylate (1) is described.
Keywords: thieno[2,3-b]thiophene; bis-heterocycles; nucleophilic addition; 2-bromo-1-phenylethanone thieno[2,3-b]thiophene; bis-heterocycles; nucleophilic addition; 2-bromo-1-phenylethanone
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Mabkhot, Y.N.; Abd Elshafy Kheder, N.; Al-Majid, A.M. Facile and Convenient Synthesis of New Thieno[2,3-b]-Thiophene Derivatives. Molecules 2010, 15, 9418-9426.

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