Next Article in Journal
Synthesis and Antitumor Activity of 3-Methyl-4-oxo-3,4-dihydroimidazo [5,1-d][1,2,3,5]tetrazine-8-carboxylates and -carboxamides
Previous Article in Journal
Synthesis of 2-(4,6-Dimethoxy-1,3,5-triazin-2-yloxyimino) Derivatives: Application in Solution Peptide Synthesis
Molecules 2010, 15(12), 9418-9426; doi:10.3390/molecules15129418
Article

Facile and Convenient Synthesis of New Thieno[2,3-b]-Thiophene Derivatives

1,* , 2,†
 and
1
1 Department of Chemistry, Faculty of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia 2 Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt Current Address: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Khalid University, Abha, Saudi Arabia
* Author to whom correspondence should be addressed.
Received: 12 October 2010 / Revised: 15 December 2010 / Accepted: 16 December 2010 / Published: 20 December 2010
Download PDF [114 KB, uploaded 18 June 2014]
SciFeed

Abstract

A facile and convenient synthesis of bis(2-(1H-benzo[d]imidazol-2(3H)-ylidene)-3-oxopropanenitrile), bis((3-amino-5-(methylthio)-1H-pyrazol-4-yl)methanone) and bis(2-thioxo-1,2-dihydropyrimidine-5-carbonitrile) derivatives incorporating a thieno- [2,3-b]thiophene moiety via versatile, readily accessible diethyl 3,4-dimethylthieno-[2,3-b]thiophene-2,5-dicarboxylate (1) is described.
Keywords: thieno[2,3-b]thiophene; bis-heterocycles; nucleophilic addition; 2-bromo-1-phenylethanone thieno[2,3-b]thiophene; bis-heterocycles; nucleophilic addition; 2-bromo-1-phenylethanone
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Mabkhot, Y.N.; Abd Elshafy Kheder, N.; Al-Majid, A.M. Facile and Convenient Synthesis of New Thieno[2,3-b]-Thiophene Derivatives. Molecules 2010, 15, 9418-9426.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert