Molecules 2010, 15(12), 8702-8708; doi:10.3390/molecules15128702
Article

Platycoside N: A New Oleanane-Type Triterpenoid Saponin from the Roots of Platycodon grandiflorum

Wei Li 1,† , Wei Zhang 1,† , Lan Xiang 2 , Zi Wang 1 , Yi-Nan Zheng 1,* email, Ying-Ping Wang 3,* email, Jing Zhang 1  and Li Chen 4
1 College of Chinese Material Medicine, Jilin Agricultural University, Changchun 130118, China 2 School of Pharmacy, Shangdong University, Jinan 250012, China 3 Institute of Special Wild Economic Animals and Plant, CAAS, Jilin 132109, China 4 Norman Bethune College of Medicine, Jilin University, Changchun 130021, China † These authors contributed equally to this work.
* Authors to whom correspondence should be addressed.
Received: 13 September 2010; in revised form: 22 November 2010 / Accepted: 25 November 2010 / Published: 30 November 2010
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Abstract: A new oleanane-type triterpenoid saponin, named platycoside N (1), together with six known saponins, was isolated from the roots of Platycodon grandiflorum. On the basis of acid hydrolysis, comprehensive spectroscopic data analyses and comparison with the spectral data of the known compounds, its structure was elucidated as 3-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-28-oic acid 28-O-β-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside. The six known compounds were platycodin D (2), deapioplatycodin D (3), platycodin D3 (4), deapio- platycodin D3 (5), platycoside E (6) and deapioplatycoside E (7).
Keywords: platycoside N; Platycodon grandiflorum; triterpenoid saponin

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Cite This Article

MDPI and ACS Style

Li, W.; Zhang, W.; Xiang, L.; Wang, Z.; Zheng, Y.-N.; Wang, Y.-P.; Zhang, J.; Chen, L. Platycoside N: A New Oleanane-Type Triterpenoid Saponin from the Roots of Platycodon grandiflorum. Molecules 2010, 15, 8702-8708.

AMA Style

Li W, Zhang W, Xiang L, Wang Z, Zheng Y-N, Wang Y-P, Zhang J, Chen L. Platycoside N: A New Oleanane-Type Triterpenoid Saponin from the Roots of Platycodon grandiflorum. Molecules. 2010; 15(12):8702-8708.

Chicago/Turabian Style

Li, Wei; Zhang, Wei; Xiang, Lan; Wang, Zi; Zheng, Yi-Nan; Wang, Ying-Ping; Zhang, Jing; Chen, Li. 2010. "Platycoside N: A New Oleanane-Type Triterpenoid Saponin from the Roots of Platycodon grandiflorum." Molecules 15, no. 12: 8702-8708.

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