Molecules 2010, 15(11), 8251-8259; doi:10.3390/molecules15118251
Article

Pancreatic Lipase Inhibition by C-Glycosidic Flavones Isolated from Eremochloa ophiuroides

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Received: 2 November 2010; in revised form: 11 November 2010 / Accepted: 12 November 2010 / Published: 16 November 2010
(This article belongs to the collection Bioactive Compounds)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Activity-guided fractionation of a methanolic extract of the leaves of Eremochloa ophiuroides (centipede grass) using a pancreatic lipase inhibitory assay led to the isolation and identification of a new C-glycosidic flavone, luteolin 6-C-b-D-boivinopyranoside (1), as well as eight known compounds. The structures of these compounds were established on the basis of interpretation of their spectroscopic data. Among these isolates, the C-glycosidic flavones 15 showed potent inhibitory effects on pancreatic lipase, with IC50 values ranging from 18.5 ± 2.6 to 50.5 ± 3.9 mM.
Keywords: Eremochloa ophiuroides; C-glycosidic flavones; obesity; pancreatic lipase
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MDPI and ACS Style

Lee, E.M.; Lee, S.S.; Chung, B.Y.; Cho, J.-Y.; Lee, I.C.; Ahn, S.R.; Jang, S.J.; Kim, T.H. Pancreatic Lipase Inhibition by C-Glycosidic Flavones Isolated from Eremochloa ophiuroides. Molecules 2010, 15, 8251-8259.

AMA Style

Lee EM, Lee SS, Chung BY, Cho J-Y, Lee IC, Ahn SR, Jang SJ, Kim TH. Pancreatic Lipase Inhibition by C-Glycosidic Flavones Isolated from Eremochloa ophiuroides. Molecules. 2010; 15(11):8251-8259.

Chicago/Turabian Style

Lee, Eun Mi; Lee, Seung Sik; Chung, Byung Yeoup; Cho, Jae-Young; Lee, In Chul; Ahn, So Ra; Jang, Soo Jeung; Kim, Tae Hoon. 2010. "Pancreatic Lipase Inhibition by C-Glycosidic Flavones Isolated from Eremochloa ophiuroides." Molecules 15, no. 11: 8251-8259.

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