Molecules 2010, 15(11), 7724-7731; doi:10.3390/molecules15117724
Article

The Knoevenagel-Doebner Reaction on 1,2-O-(2,2,2-Trichloroethylidene) Derivatives of D-Gluco- and D-Manno- furanose†

Gökhan Kök 1 email, Tamer Karayıldırım 1 email, Kadir Ay 2 email and Emriye Ay 2,* email
1 Chemistry Department, Faculty of Science, Ege University, Bornova, İzmir 35100, Turkey 2 Chemistry Department, Faculty of Arts and Sciences, Celal Bayar University, Campus of Muradiye, Manisa 45030, Turkey
† Initial data was presented at the 11th International Electronic Conference on Synthetic Organic Chemistry, ECSOC-11, 1-30 November 2007, paper a007.
* Author to whom correspondence should be addressed.
Received: 8 October 2010; in revised form: 25 October 2010 / Accepted: 28 October 2010 / Published: 29 October 2010
PDF Full-text Download PDF Full-Text [251 KB, uploaded 1 November 2010 14:35 CET]
Abstract: The synthesis of new α,β-unsaturated furanuronic acid derivatives of α-gluco- (3), β-gluco- (6) and β-manno-chloraloses (9) via a convenient one pot procedure using the Knoevenagel-Doebner reaction approach are described. The dialdofuranose derivatives were reacted with malonic acid under Knoevenagel-Doebner reaction conditions and (E)-α,β-unsaturated furanuronic acid derivatives were obtained.
Keywords: chloralose; trichloroethylidene; dialdofuranose; Knoevenagel-Doebner reaction; sugar chain extension

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Kök, G.; Karayıldırım, T.; Ay, K.; Ay, E. The Knoevenagel-Doebner Reaction on 1,2-O-(2,2,2-Trichloroethylidene) Derivatives of D-Gluco- and D-Manno- furanose. Molecules 2010, 15, 7724-7731.

AMA Style

Kök G, Karayıldırım T, Ay K, Ay E. The Knoevenagel-Doebner Reaction on 1,2-O-(2,2,2-Trichloroethylidene) Derivatives of D-Gluco- and D-Manno- furanose. Molecules. 2010; 15(11):7724-7731.

Chicago/Turabian Style

Kök, Gökhan; Karayıldırım, Tamer; Ay, Kadir; Ay, Emriye. 2010. "The Knoevenagel-Doebner Reaction on 1,2-O-(2,2,2-Trichloroethylidene) Derivatives of D-Gluco- and D-Manno- furanose." Molecules 15, no. 11: 7724-7731.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert