Next Article in Journal
Lead Contamination in Selected Foods from Riyadh City Market and Estimation of the Daily Intake
Previous Article in Journal
A New Natural Ceramide from Trollius chinensis Bunge
Molecules 2010, 15(10), 7472-7481; doi:10.3390/molecules15107472
Article

Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes

1,* , 1
, 2
 and 3,*
1 College of Pharmaceutical and Chemical Engineering, Taizhou University, Linhai 317000, China 2 Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China 3 Ningbo Institute of Material Technology and Engineering, Chinese Academy of Sciences, Ningbo 315211, China
* Authors to whom correspondence should be addressed.
Received: 7 September 2010 / Revised: 29 September 2010 / Accepted: 2 October 2010 / Published: 25 October 2010
Download PDF [117 KB, uploaded 18 June 2014]

Abstract

A series of novel 1-[(2,6-dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes 6a-i were synthesized using the Vilsmeier-Haack reagent. The structures of all the title compounds have been confirmed by elemental analysis, 1H-NMR and 13C-NMR and in addition, the structure of intermediate 5b was investigated by X-ray crystallography.
Keywords: Vilsmeier-Haack reagent; phenylhydrazine; phenylhydrazone; 1H-pyrazole-4-carbaldehyde Vilsmeier-Haack reagent; phenylhydrazine; phenylhydrazone; 1H-pyrazole-4-carbaldehyde
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Export to BibTeX |
EndNote


MDPI and ACS Style

Hu, H.; Ge, C.; Ding, L.; Zhang, A. Synthesis of Novel 1-[(2,6-Dichloro-4-trifluoromethyl)phenyl]-3-aryl-1H-pyrazole-4-carbaldehydes. Molecules 2010, 15, 7472-7481.

View more citation formats

Related Articles

Article Metrics

Comments

Citing Articles

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert