Molecules 2010, 15(10), 7235-7265; doi:10.3390/molecules15107235
Review

Protecting Groups in Carbohydrate Chemistry: Influence on Stereoselectivity of Glycosylations

Received: 5 September 2010; Accepted: 15 October 2010 / Published: 20 October 2010
(This article belongs to the Special Issue Protecting Group in Organic Synthesis)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Saccharides are polyhydroxy compounds, and their synthesis requires complex protecting group manipulations. Protecting groups are usually used to temporarily mask a functional group which may interfere with a certain reaction, but protecting groups in carbohydrate chemistry do more than protecting groups usually do. Particularly, protecting groups can participate in reactions directly or indirectly, thus affecting the stereochemical outcomes, which is important for synthesis of oligosaccharides. Herein we present an overview of recent advances in protecting groups influencing stereoselectivity in glycosylation reactions, including participating protecting groups, and conformation-constraining protecting groups in general.
Keywords: protecting group; stereoselectivity; glycosylation; carbohydrate
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MDPI and ACS Style

Guo, J.; Ye, X.-S. Protecting Groups in Carbohydrate Chemistry: Influence on Stereoselectivity of Glycosylations. Molecules 2010, 15, 7235-7265.

AMA Style

Guo J, Ye X-S. Protecting Groups in Carbohydrate Chemistry: Influence on Stereoselectivity of Glycosylations. Molecules. 2010; 15(10):7235-7265.

Chicago/Turabian Style

Guo, Jian; Ye, Xin-Shan. 2010. "Protecting Groups in Carbohydrate Chemistry: Influence on Stereoselectivity of Glycosylations." Molecules 15, no. 10: 7235-7265.

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