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A correction was published on 10 November 2010, see Molecules 2010, 15(11), 8143.

Molecules 2010, 15(10), 7016-7034; doi:10.3390/molecules15107016
Article

Synthesis and Reactivity of [1,2,4]Triazolo-annelated Quinazolines

Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
Received: 25 September 2010 / Revised: 29 September 2010 / Accepted: 8 October 2010 / Published: 12 October 2010
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Abstract

This paper reports the synthesis of phenyl-substituted 2-alkoxy(methylsulfanyl)-1,2,4-triazolo[1,5-a]quinazolines starting from N-cyanoimidocarbonates and substituted hydrazinobenzoic acids as building blocks. Thionation or chlorination of the inherent lactam moiety in the target compounds followed by treatment with multifunctional nucleophiles provided access to a variety of derivatives.
Keywords: triazolo[1,5-a]quinazolines; thionation; alkylation; chlorination; tetracyclic systems triazolo[1,5-a]quinazolines; thionation; alkylation; chlorination; tetracyclic systems
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Al-Salahi, R.A. Synthesis and Reactivity of [1,2,4]Triazolo-annelated Quinazolines. Molecules 2010, 15, 7016-7034.

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