Solvent Free, Microwave Assisted Conversion of Aldehydes into Nitriles and Oximes in the Presence of NH2OH·HCl and TiO2

doi:10.3390/molecules15010094

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Molecules 2010, 15(1), 94-99; doi:10.3390/molecules15010094

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Solvent Free, Microwave Assisted Conversion of Aldehydes into Nitriles and Oximes in the Presence of NH₂OH·HCl and TiO₂

Lucas Villas-Boas Hoelz, Biank Tomaz Gonçalves, José Celestino Barros and Joaquim Fernando Mendes da Silva*

Departamento de Química Orgânica, Instituto de Química, Universidade Federal do Rio de Janeiro, Av. Athos da Silveira Ramos 149, CT Bloco A, Cidade Universitária, Rio de Janeiro, RJ 21941-909, RJ, Brazil

* Author to whom correspondence should be addressed.

Received: 27 October 2009; in revised form: 22 December 2009 / Accepted: 23 December 2009 / Published: 29 December 2009

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Abstract: Aromatic aldehydes bearing electron-donating groups are easily converted into their respective nitriles using NH₂OH·HCl and TiO₂ under microwave irradiation, while those bearing an electron-withdrawing group give the corresponding oximes.

Keywords: titanium dioxide; aldehydes; nitriles; oximes; microwave irradiation

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MDPI and ACS Style

Villas-Boas Hoelz, L.; Gonçalves, B.T.; Barros, J.C.; Mendes da Silva, J.F. Solvent Free, Microwave Assisted Conversion of Aldehydes into Nitriles and Oximes in the Presence of NH₂OH·HCl and TiO₂. Molecules 2010, 15, 94-99.

AMA Style

Villas-Boas Hoelz L, Gonçalves BT, Barros JC, Mendes da Silva JF. Solvent Free, Microwave Assisted Conversion of Aldehydes into Nitriles and Oximes in the Presence of NH₂OH·HCl and TiO₂. Molecules. 2010; 15(1):94-99.

Chicago/Turabian Style

Villas-Boas Hoelz, Lucas; Gonçalves, Biank Tomaz; Barros, José Celestino; Mendes da Silva, Joaquim Fernando. 2010. "Solvent Free, Microwave Assisted Conversion of Aldehydes into Nitriles and Oximes in the Presence of NH₂OH·HCl and TiO₂." Molecules 15, no. 1: 94-99.

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