Next Article in Journal
Previous Article in Journal
Molecules 2009, 14(7), 2431-2446; doi:10.3390/molecules14072431
Article

Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives

Received: 17 May 2009; in revised form: 12 June 2009 / Accepted: 6 July 2009 / Published: 8 July 2009
Download PDF [191 KB, uploaded 18 June 2014]
Abstract: New imidazole ring derivatives comprising 1,3-oxazoline, Schiff's bases, thiadiazole, oxadiazole and 1,2,4-triazole moieties are reported. 3-Aminobiimidazol-4-one compounds 7a-c were synthesized by the reaction of compounds 6a-c with hydrazine hydrate. Biimidazole esters 9a-c were converted into biimidazole hydrazide esters 10a-c. Compounds 7a-c and 10a-c were converted into a variety of derivatives.
Keywords: metronidazole; biimidazole; imidazole; 1; 3; 4-oxadiazole; 1; 2; 4-triazole; 1; 3; 4-thiadiazole metronidazole; biimidazole; imidazole; 1; 3; 4-oxadiazole; 1; 2; 4-triazole; 1; 3; 4-thiadiazole
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Atia, A.J.K. Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives. Molecules 2009, 14, 2431-2446.

AMA Style

Atia AJK. Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives. Molecules. 2009; 14(7):2431-2446.

Chicago/Turabian Style

Atia, Abdul Jabar Kh. 2009. "Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives." Molecules 14, no. 7: 2431-2446.



Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert