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Molecules 2009, 14(6), 2127-2134; doi:10.3390/molecules14062127

Effect of Ionic Liquids as the Mobile Phase Additives on the HPLC Resolution of Four Active Compounds from Sophora flavescens Ait

Department of Chemical Engineering, Inha University, Incheon, 402–751, Korea
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Author to whom correspondence should be addressed.
Received: 17 April 2009 / Revised: 7 May 2009 / Accepted: 2 June 2009 / Published: 11 June 2009
(This article belongs to the Special Issue Ionic Liquids)
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Abstract

The retention behaviour of four active compounds from Sophora Flavescens Ait using three ionic liquids as mobile phase modifiers was examined. The effect of the pH and the amount of ionic liquid modifier on the retention of these compounds was determined in methanol/water (v/v) as the mobile phase containing different ionic liquids ranging in concentration from 0.1 mmol/L to 3.0 mmol/L. The ionic liquids showed promise as additives in high-performance liquid chromatography.
Keywords: ionic liquid; retention; resolution; HPLC; Sophora flavescens Ait ionic liquid; retention; resolution; HPLC; Sophora flavescens Ait
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Tian, M.; Liu, J.; Row, K.H. Effect of Ionic Liquids as the Mobile Phase Additives on the HPLC Resolution of Four Active Compounds from Sophora flavescens Ait. Molecules 2009, 14, 2127-2134.

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