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Molecules 2009, 14(4), 1537-1545; doi:10.3390/molecules14041537
Article

Determination of Proton Relaxivities of Mn(II), Cu(II) and Cr(III) added to Solutions of Serum Proteins

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Received: 26 February 2009; in revised form: 18 March 2009 / Accepted: 10 April 2009 / Published: 14 April 2009
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Abstract: Relaxometric studies are still of scientific interest due to their use in medicine and biology. In this study, proton T1 and T2 relaxivities of Mn(II), Cu(II) and Cr(III) in water were determined in the presence and absence of various proteins (albumin, α-globulin, γ-globulin, lysozyme, fibrinogen). The 1/T1 and 1/T2 in all solutions are linearly proportional to the concentration of the paramagnetic ions. Mn(II) has the great influence to alter relaxations in all protein solutions, while Cu(II) and Cr(III) have a poor influence on the relaxations. In addition, Mn(II) and Cu(II) are bound to each protein, but Cr(III) is not bound to any protein.
Keywords: MRI; T1; T2; Mn(II); Cu(II); Cr(III); Serum proteins MRI; T1; T2; Mn(II); Cu(II); Cr(III); Serum proteins
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MDPI and ACS Style

Köylü, M.Z.; Asubay, S.; Yilmaz, A. Determination of Proton Relaxivities of Mn(II), Cu(II) and Cr(III) added to Solutions of Serum Proteins. Molecules 2009, 14, 1537-1545.

AMA Style

Köylü MZ, Asubay S, Yilmaz A. Determination of Proton Relaxivities of Mn(II), Cu(II) and Cr(III) added to Solutions of Serum Proteins. Molecules. 2009; 14(4):1537-1545.

Chicago/Turabian Style

Köylü, Mehmet Zafer; Asubay, Sezai; Yilmaz, Ali. 2009. "Determination of Proton Relaxivities of Mn(II), Cu(II) and Cr(III) added to Solutions of Serum Proteins." Molecules 14, no. 4: 1537-1545.


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