Determination of Proton Relaxivities of Mn(II), Cu(II) and Cr(III) added to Solutions of Serum Proteins

doi:10.3390/molecules14041537

This article is

freely available
re-usable

Molecules 2009, 14(4), 1537-1545; doi:10.3390/molecules14041537

Article

Determination of Proton Relaxivities of Mn(II), Cu(II) and Cr(III) added to Solutions of Serum Proteins

Mehmet Zafer Köylü* , Sezai Asubay and Ali Yilmaz

Department of Physics, University of Dicle, 21280 Diyarbakir, Turkey

* Author to whom correspondence should be addressed.

Received: 26 February 2009; in revised form: 18 March 2009 / Accepted: 10 April 2009 / Published: 14 April 2009

Download PDF Full-Text [199 KB, uploaded 14 April 2009 15:07 CEST]

Abstract: Relaxometric studies are still of scientific interest due to their use in medicine and biology. In this study, proton T₁ and T₂ relaxivities of Mn(II), Cu(II) and Cr(III) in water were determined in the presence and absence of various proteins (albumin, α-globulin, γ-globulin, lysozyme, fibrinogen). The 1/T₁ and 1/T₂ in all solutions are linearly proportional to the concentration of the paramagnetic ions. Mn(II) has the great influence to alter relaxations in all protein solutions, while Cu(II) and Cr(III) have a poor influence on the relaxations. In addition, Mn(II) and Cu(II) are bound to each protein, but Cr(III) is not bound to any protein.

Keywords: MRI; T1; T2; Mn(II); Cu(II); Cr(III); Serum proteins

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Köylü, M.Z.; Asubay, S.; Yilmaz, A. Determination of Proton Relaxivities of Mn(II), Cu(II) and Cr(III) added to Solutions of Serum Proteins. Molecules 2009, 14, 1537-1545.

AMA Style

Köylü MZ, Asubay S, Yilmaz A. Determination of Proton Relaxivities of Mn(II), Cu(II) and Cr(III) added to Solutions of Serum Proteins. Molecules. 2009; 14(4):1537-1545.

Chicago/Turabian Style

Köylü, Mehmet Zafer; Asubay, Sezai; Yilmaz, Ali. 2009. "Determination of Proton Relaxivities of Mn(II), Cu(II) and Cr(III) added to Solutions of Serum Proteins." Molecules 14, no. 4: 1537-1545.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert