Next Article in Journal
Previous Article in Journal
Molecular Docking Studies and Anti-enzymatic Activities of Thai Mango Seed Kernel Extract Against Snake Venoms
Molecules 2009, 14(4), 1423-1428; doi:10.3390/molecules14041423

Ultrasound Promoted Synthesis of Bis(substituted pyrazol-4-ylcarbonyl)-Substituted Thioureas

School of Chemistry and Chemical Engineering, Xinjiang University, Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education, 830046 Urumqi, P. R. China
* Author to whom correspondence should be addressed.
Received: 28 February 2009 / Revised: 15 March 2009 / Accepted: 23 March 2009 / Published: 31 March 2009
View Full-Text   |   Download PDF [200 KB, uploaded 18 June 2014]   |  


A series of novel bis(substituted pyrazol-4-ylcarbonyl)-substituted thioureas have been synthesized by the reactions of substituted pyrazol-4-ylcarbonyl isothiocyanates with different diamines under ultrasound irradiation and classical heating method at 20-25 °C. In general, substantial improvement in rates and modest yields increases were observed when reactions were carried out under sonication, compared with the classical heating method. The structures of these compounds have been elucidated by elemental and spectral (IR, 1H-NMR) analysis.
Keywords: Thiourea; Pyrazole; Diamine; Ultrasound; Synthesis Thiourea; Pyrazole; Diamine; Ultrasound; Synthesis
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
MDPI and ACS Style

Xiao, L.; Liu, C.-J.; Li, Y.-P. Ultrasound Promoted Synthesis of Bis(substituted pyrazol-4-ylcarbonyl)-Substituted Thioureas. Molecules 2009, 14, 1423-1428.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert