Molecules 2009, 14(4), 1389-1395; doi:10.3390/molecules14041389
Article

Antimalarial and Cytotoxic Phenolic Compounds from Cratoxylum maingayi and Cratoxylum cochinchinense

1 School of Science, Mae Fah Luang University; Tasud, Muang, Chiang Rai 57100, Thailand 2 Faculty of Science and Industrial Technology, Prince of Songkla University, Muang, Suratthani, Thailand
* Authors to whom correspondence should be addressed.
Received: 13 February 2009; in revised form: 23 March 2009 / Accepted: 23 March 2009 / Published: 30 March 2009
PDF Full-text Download PDF Full-Text [102 KB, uploaded 14 April 2009 09:05 CEST]
Abstract: Nine phenolic compounds isolated from Cratoxylum maingayi and C. cochinchinense were evaluated for anti-malarial activity against Plasmodium falciparum, and for cytotoxic activity against the NCI-H187 (human small cell lung cancer) cancer cell line. Formoxanthone C (3) was found to be the most active against the NCI-H187 cancer cell line, with an IC50 of 0.22 mg/mL, while vismione B (7) had the highest activity against Plasmodium falciparum, with an IC50 of 0.66 mg/mL.
Keywords: Cratoxylum maingayi; C. cochinchinense; Xanthones; Anti-malarial activity; Cytotoxic activity

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Laphookhieo, S.; Maneerat, W.; Koysomboon, S. Antimalarial and Cytotoxic Phenolic Compounds from Cratoxylum maingayi and Cratoxylum cochinchinense. Molecules 2009, 14, 1389-1395.

AMA Style

Laphookhieo S, Maneerat W, Koysomboon S. Antimalarial and Cytotoxic Phenolic Compounds from Cratoxylum maingayi and Cratoxylum cochinchinense. Molecules. 2009; 14(4):1389-1395.

Chicago/Turabian Style

Laphookhieo, Surat; Maneerat, Wisanu; Koysomboon, Sorwaporn. 2009. "Antimalarial and Cytotoxic Phenolic Compounds from Cratoxylum maingayi and Cratoxylum cochinchinense." Molecules 14, no. 4: 1389-1395.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert