Next Article in Journal
A New Insecticidal Sesquiterpene Ester from Celastrus Angulatus
Previous Article in Journal
Syntheses, Spectroscopic and AFM Characterization of Some Manganese Porphyrins and Their Hybrid Silica Nanomaterials
Article Menu

Export Article

Open AccessArticle
Molecules 2009, 14(4), 1389-1395; doi:10.3390/molecules14041389

Antimalarial and Cytotoxic Phenolic Compounds from Cratoxylum maingayi and Cratoxylum cochinchinense

1
School of Science, Mae Fah Luang University; Tasud, Muang, Chiang Rai 57100, Thailand
2
Faculty of Science and Industrial Technology, Prince of Songkla University, Muang, Suratthani, Thailand
*
Authors to whom correspondence should be addressed.
Received: 13 February 2009 / Revised: 23 March 2009 / Accepted: 23 March 2009 / Published: 30 March 2009
View Full-Text   |   Download PDF [102 KB, uploaded 18 June 2014]   |  

Abstract

Nine phenolic compounds isolated from Cratoxylum maingayi and C. cochinchinense were evaluated for anti-malarial activity against Plasmodium falciparum, and for cytotoxic activity against the NCI-H187 (human small cell lung cancer) cancer cell line. Formoxanthone C (3) was found to be the most active against the NCI-H187 cancer cell line, with an IC50 of 0.22 mg/mL, while vismione B (7) had the highest activity against Plasmodium falciparum, with an IC50 of 0.66 mg/mL. View Full-Text
Keywords: Cratoxylum maingayi; C. cochinchinense; Xanthones; Anti-malarial activity; Cytotoxic activity Cratoxylum maingayi; C. cochinchinense; Xanthones; Anti-malarial activity; Cytotoxic activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Laphookhieo, S.; Maneerat, W.; Koysomboon, S. Antimalarial and Cytotoxic Phenolic Compounds from Cratoxylum maingayi and Cratoxylum cochinchinense. Molecules 2009, 14, 1389-1395.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top