Molecules 2009, 14(3), 917-924; doi:10.3390/molecules14030917
Article

Total Syntheses of Telisatin A, Telisatin B and Lettowianthine

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Received: 2 February 2009; in revised form: 17 February 2009 / Accepted: 26 February 2009 / Published: 26 February 2009
(This article belongs to the Special Issue Aporphines and Oxoaporphines)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Treatment of 1-(2-bromoarylmethyl)-3,4-dihydroisoquinolines with oxalyl chloride and triethylamine gave 1-(2-bromophenyl)-5,6-dihydropyrrolo[2,1-a]isoquinoline-2,3-dione derivatives, for example, 1-(2-bromophenyl)-5,6-dihydro-8,9-dimethoxypyrrolo[2,1-a]isoquinoline-2,3-dione. Radical cyclisation of these derivatives with tributyltin hydride and 1,1-azobis(cyclohexanecarbonitrile) afforded telisatin A, telisatin B and lettowianthine.
Keywords: Alkaloid; Dioxoaporphine; Isoquinoline; Radical cyclisation; Synthesis
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MDPI and ACS Style

Nimgirawath, S.; Udomputtimekakul, P. Total Syntheses of Telisatin A, Telisatin B and Lettowianthine. Molecules 2009, 14, 917-924.

AMA Style

Nimgirawath S, Udomputtimekakul P. Total Syntheses of Telisatin A, Telisatin B and Lettowianthine. Molecules. 2009; 14(3):917-924.

Chicago/Turabian Style

Nimgirawath, Surachai; Udomputtimekakul, Phansuang. 2009. "Total Syntheses of Telisatin A, Telisatin B and Lettowianthine." Molecules 14, no. 3: 917-924.

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