Molecules 2009, 14(3), 917-924; doi:10.3390/molecules14030917
Total Syntheses of Telisatin A, Telisatin B and Lettowianthine
Department of Chemistry, Faculty of Science, Silpakorn University; Nakorn Pathom 73000, Thailand
*
Author to whom correspondence should be addressed.
Received: 2 February 2009 / Revised: 17 February 2009 / Accepted: 26 February 2009 / Published: 26 February 2009
(This article belongs to the Special Issue Aporphines and Oxoaporphines)
Abstract
Treatment of 1-(2-bromoarylmethyl)-3,4-dihydroisoquinolines with oxalyl chloride and triethylamine gave 1-(2-bromophenyl)-5,6-dihydropyrrolo[2,1-a]isoquinoline-2,3-dione derivatives, for example, 1-(2-bromophenyl)-5,6-dihydro-8,9-dimethoxypyrrolo[2,1-a]isoquinoline-2,3-dione. Radical cyclisation of these derivatives with tributyltin hydride and 1,1-azobis(cyclohexanecarbonitrile) afforded telisatin A, telisatin B and lettowianthine. View Full-TextKeywords:
Alkaloid; Dioxoaporphine; Isoquinoline; Radical cyclisation; Synthesis
▼
Figures
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
Scifeed alert for new publications
Never miss any articles matching your research from any publisher- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Share & Cite This Article
MDPI and ACS Style
Nimgirawath, S.; Udomputtimekakul, P. Total Syntheses of Telisatin A, Telisatin B and Lettowianthine. Molecules 2009, 14, 917-924.
Related Articles
Article Metrics
Comments
Molecules
EISSN 1420-3049
Published by MDPI AG, Basel, Switzerland
RSS
E-Mail Table of Contents Alert