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Molecules 2009, 14(12), 5382-5388; doi:10.3390/molecules14125382
Article

New Conjugated Benzothiazole-N-oxides: Synthesis and Biological Activity

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Received: 28 October 2009; in revised form: 12 December 2009 / Accepted: 18 December 2009 / Published: 23 December 2009
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Abstract: Eleven new 2-styrylbenzothiazole-N-oxides have been prepared by aldol – type condensation reactions between 2-methylbenzothiazole–N-oxide and para-substituted benzaldehydes. Compounds with cyclic amino substituents showed typical push-pull molecule properties. Four compounds were tested against various bacterial strains as well as the protozoan Euglena gracilis as model microorganisms. Unlike previously prepared analogous benzothiazolium salts, only weak activity was recorded.
Keywords: benzothiazole; N-oxides; push-pull systems; antibacterial; Euglena gracilis benzothiazole; N-oxides; push-pull systems; antibacterial; Euglena gracilis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Gajdoš, P.; Magdolen, P.; Zahradník, P.; Foltínová, P. New Conjugated Benzothiazole-N-oxides: Synthesis and Biological Activity. Molecules 2009, 14, 5382-5388.

AMA Style

Gajdoš P, Magdolen P, Zahradník P, Foltínová P. New Conjugated Benzothiazole-N-oxides: Synthesis and Biological Activity. Molecules. 2009; 14(12):5382-5388.

Chicago/Turabian Style

Gajdoš, Peter; Magdolen, Peter; Zahradník, Pavol; Foltínová, Pavlína. 2009. "New Conjugated Benzothiazole-N-oxides: Synthesis and Biological Activity." Molecules 14, no. 12: 5382-5388.



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