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Molecules 2009, 14(1), 566-572; doi:10.3390/molecules14010566

Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia

1
College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, 130118, P.R. China
2
Institute of Agricultural Modernization, Jilin Agricultural University, Changchun, 130118, P.R. China
3
Research Centre for Medical and Structural Biology, School of Basic Medical Science, Wuhan University, Wuhan, 430071, P.R. China
*
Author to whom correspondence should be addressed.
Received: 20 November 2008 / Revised: 13 January 2009 / Accepted: 15 January 2009 / Published: 23 January 2009
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Abstract

A new anthraquinone, Rubiacordone A (1) (6-acetoxy-1-hydroxy-2-methylanthraquinone-3-O-α-L-rhamnopyranoside), was isolated together with the known anthraquinone, 1-acetoxy-6-hydroxy-2-methylanthraquinone-3-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] (2), from the dried roots of Rubia cordifolia. Their structures were elucidated on the basis of extensive 1D and 2D-NMR, as well as HRESI-MS spectroscopic analysis. Metabolites 1 and 2 showed considerable antimicrobial activity against Gram-positive bacteria.
Keywords: Rubia cordifolia; Rubiacordone A; Anthraquinone; Antimicrobial Rubia cordifolia; Rubiacordone A; Anthraquinone; Antimicrobial
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Li, X.; Liu, Z.; Chen, Y.; Wang, L.-J.; Zheng, Y.-N.; Sun, G.-Z.; Ruan, C.-C. Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia. Molecules 2009, 14, 566-572.

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