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Molecules 2009, 14(1), 566-572; doi:10.3390/molecules14010566
Communication

Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia

1
, 2
, 3
, 1
, 1
, 2
 and 2,*
1 College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, 130118, P.R. China 2 Institute of Agricultural Modernization, Jilin Agricultural University, Changchun, 130118, P.R. China 3 Research Centre for Medical and Structural Biology, School of Basic Medical Science, Wuhan University, Wuhan, 430071, P.R. China
* Author to whom correspondence should be addressed.
Received: 20 November 2008 / Revised: 13 January 2009 / Accepted: 15 January 2009 / Published: 23 January 2009
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Abstract

A new anthraquinone, Rubiacordone A (1) (6-acetoxy-1-hydroxy-2-methylanthraquinone-3-O-α-L-rhamnopyranoside), was isolated together with the known anthraquinone, 1-acetoxy-6-hydroxy-2-methylanthraquinone-3-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] (2), from the dried roots of Rubia cordifolia. Their structures were elucidated on the basis of extensive 1D and 2D-NMR, as well as HRESI-MS spectroscopic analysis. Metabolites 1 and 2 showed considerable antimicrobial activity against Gram-positive bacteria.
Keywords: Rubia cordifolia; Rubiacordone A; Anthraquinone; Antimicrobial Rubia cordifolia; Rubiacordone A; Anthraquinone; Antimicrobial
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Li, X.; Liu, Z.; Chen, Y.; Wang, L.-J.; Zheng, Y.-N.; Sun, G.-Z.; Ruan, C.-C. Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia. Molecules 2009, 14, 566-572.

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