Open AccessThis article is
- freely available
Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia
College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, 130118, P.R. China
Institute of Agricultural Modernization, Jilin Agricultural University, Changchun, 130118, P.R. China
Research Centre for Medical and Structural Biology, School of Basic Medical Science, Wuhan University, Wuhan, 430071, P.R. China
* Author to whom correspondence should be addressed.
Received: 20 November 2008; in revised form: 13 January 2009 / Accepted: 15 January 2009 / Published: 23 January 2009
Abstract: A new anthraquinone, Rubiacordone A (1) (6-acetoxy-1-hydroxy-2-methylanthraquinone-3-O-α-L-rhamnopyranoside), was isolated together with the known anthraquinone, 1-acetoxy-6-hydroxy-2-methylanthraquinone-3-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] (2), from the dried roots of Rubia cordifolia. Their structures were elucidated on the basis of extensive 1D and 2D-NMR, as well as HRESI-MS spectroscopic analysis. Metabolites 1 and 2 showed considerable antimicrobial activity against Gram-positive bacteria.
Keywords: Rubia cordifolia; Rubiacordone A; Anthraquinone; Antimicrobial
Article StatisticsClick here to load and display the download statistics.
Notes: Multiple requests from the same IP address are counted as one view.
Cite This Article
MDPI and ACS Style
Li, X.; Liu, Z.; Chen, Y.; Wang, L.-J.; Zheng, Y.-N.; Sun, G.-Z.; Ruan, C.-C. Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia. Molecules 2009, 14, 566-572.
Li X, Liu Z, Chen Y, Wang L-J, Zheng Y-N, Sun G-Z, Ruan C-C. Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia. Molecules. 2009; 14(1):566-572.
Li, Xiang; Liu, Zhi; Chen, Yun; Wang, Li-Juan; Zheng, Yi-Nan; Sun, Guang-Zhi; Ruan, Chang-Chun. 2009. "Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia." Molecules 14, no. 1: 566-572.