Molecules 2009, 14(1), 474-479; doi:10.3390/molecules14010474
Article

Mechanochemical Solvent-Free and Catalyst-Free One-Pot Synthesis of Pyrano[2,3-d]Pyrimidine-2,4(1H,3H)-Diones with Quantitative Yields

Organic Chemistry Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846 Tehran, Iran
* Author to whom correspondence should be addressed.
Received: 26 November 2008; in revised form: 13 January 2009 / Accepted: 14 January 2009 / Published: 19 January 2009
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Abstract: Solvent-free synthesis of pyrano[2,3-d]pyrimidine-2,4(1H,3H)-diones by ball-milling and without any catalyst is described. This method provides several advantages such as being environmentally friendly, using a simple workup procedure, and affording high yields.
Keywords: Solvent-free reaction; Barbituric acid; Pyrimidinediones; Heterocyclic compounds; Ball-milling

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MDPI and ACS Style

Mashkouri, S.; Reza Naimi-Jamal, M. Mechanochemical Solvent-Free and Catalyst-Free One-Pot Synthesis of Pyrano[2,3-d]Pyrimidine-2,4(1H,3H)-Diones with Quantitative Yields. Molecules 2009, 14, 474-479.

AMA Style

Mashkouri S, Reza Naimi-Jamal M. Mechanochemical Solvent-Free and Catalyst-Free One-Pot Synthesis of Pyrano[2,3-d]Pyrimidine-2,4(1H,3H)-Diones with Quantitative Yields. Molecules. 2009; 14(1):474-479.

Chicago/Turabian Style

Mashkouri, Sara; Reza Naimi-Jamal, M. 2009. "Mechanochemical Solvent-Free and Catalyst-Free One-Pot Synthesis of Pyrano[2,3-d]Pyrimidine-2,4(1H,3H)-Diones with Quantitative Yields." Molecules 14, no. 1: 474-479.

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