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Correction: Wang, Z.-N., et al. A New Cytotoxic Pregnanone from Calotropis gigantean. Molecules 2008, 13, 3033-3039.
Molecules 2009, 14(1), 414-422; doi:10.3390/molecules14010414
Communication

A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha

1, 1,* , 2, 2, 1, 1 and 3
1 Key Laboratory of Ministry of Education for Coastal and Wetland Ecosystems, School of Life Sciences, Xiamen University, Xiamen 361005, China 2 College of Oceanography and Environmental Science, Xiamen University, Xiamen 361005, China 3 The Third Institute of Oceanography State Oceanic Administration, Xiamen 361005, China
* Author to whom correspondence should be addressed.
Received: 26 October 2008 / Revised: 13 January 2009 / Accepted: 15 January 2009 / Published: 16 January 2009
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Abstract

A new atisane-type diterpene, ent-16α-hydroxy-atisane-3,4-lactone (4) and three known diterpenes, ent-16α-hydroxy-atisane-3-one (1), ent-atisane-3β,16α-diol (2), ent-3,4-seco-16α-hydroxyatis- 4(19)-en -3-oic acid (3) were isolated from the bark of the mangrove plant Excoecaria agallocha. Their structures and relative stereochemistry were elucidated by means of extensive NMR and MS analysis. Compound 3 exhibited significant anti-microfouling activity against the adherence of Pseudomonas pseudoalcaligenes, with an EC50 value of 0.54 ± 0.01 ppm.
Keywords: Diterpenes; Biofilm; Excoecaria agallocha; Anti-microfouling Diterpenes; Biofilm; Excoecaria agallocha; Anti-microfouling
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Wang, Z.C.; Lin, Y.M.; Feng, D.Q.; Ke, C.H.; Lin, P.; Yan, C.L.; Chen, J.D. A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha. Molecules 2009, 14, 414-422.

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