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Molecules 2009, 14(1), 414-422; doi:10.3390/molecules14010414
Communication

A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha

1, 1,* , 2, 2, 1, 1 and 3
Received: 26 October 2008; in revised form: 13 January 2009 / Accepted: 15 January 2009 / Published: 16 January 2009
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Abstract: A new atisane-type diterpene, ent-16α-hydroxy-atisane-3,4-lactone (4) and three known diterpenes, ent-16α-hydroxy-atisane-3-one (1), ent-atisane-3β,16α-diol (2), ent-3,4-seco-16α-hydroxyatis- 4(19)-en -3-oic acid (3) were isolated from the bark of the mangrove plant Excoecaria agallocha. Their structures and relative stereochemistry were elucidated by means of extensive NMR and MS analysis. Compound 3 exhibited significant anti-microfouling activity against the adherence of Pseudomonas pseudoalcaligenes, with an EC50 value of 0.54 ± 0.01 ppm.
Keywords: Diterpenes; Biofilm; Excoecaria agallocha; Anti-microfouling Diterpenes; Biofilm; Excoecaria agallocha; Anti-microfouling
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Wang, Z.C.; Lin, Y.M.; Feng, D.Q.; Ke, C.H.; Lin, P.; Yan, C.L.; Chen, J.D. A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha. Molecules 2009, 14, 414-422.

AMA Style

Wang ZC, Lin YM, Feng DQ, Ke CH, Lin P, Yan CL, Chen JD. A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha. Molecules. 2009; 14(1):414-422.

Chicago/Turabian Style

Wang, Zhan Chang; Lin, Yi Ming; Feng, Dan Qin; Ke, Cai Huan; Lin, Peng; Yan, Chong Ling; Chen, Jun De. 2009. "A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha." Molecules 14, no. 1: 414-422.



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