A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha
AbstractA new atisane-type diterpene, ent-16α-hydroxy-atisane-3,4-lactone (4) and three known diterpenes, ent-16α-hydroxy-atisane-3-one (1), ent-atisane-3β,16α-diol (2), ent-3,4-seco-16α-hydroxyatis- 4(19)-en -3-oic acid (3) were isolated from the bark of the mangrove plant Excoecaria agallocha. Their structures and relative stereochemistry were elucidated by means of extensive NMR and MS analysis. Compound 3 exhibited significant anti-microfouling activity against the adherence of Pseudomonas pseudoalcaligenes, with an EC50 value of 0.54 ± 0.01 ppm.
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Wang, Z.C.; Lin, Y.M.; Feng, D.Q.; Ke, C.H.; Lin, P.; Yan, C.L.; Chen, J.D. A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha. Molecules 2009, 14, 414-422.
Wang ZC, Lin YM, Feng DQ, Ke CH, Lin P, Yan CL, Chen JD. A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha. Molecules. 2009; 14(1):414-422.Chicago/Turabian Style
Wang, Zhan Chang; Lin, Yi Ming; Feng, Dan Qin; Ke, Cai Huan; Lin, Peng; Yan, Chong Ling; Chen, Jun De. 2009. "A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha." Molecules 14, no. 1: 414-422.