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Correction: Wang, Z.-N., et al. A New Cytotoxic Pregnanone from Calotropis gigantean. Molecules 2008, 13, 3033-3039.
Molecules 2009, 14(1), 414-422; doi:10.3390/molecules14010414
Communication

A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha

1, 1,* , 2, 2, 1, 1 and 3
1 Key Laboratory of Ministry of Education for Coastal and Wetland Ecosystems, School of Life Sciences, Xiamen University, Xiamen 361005, China 2 College of Oceanography and Environmental Science, Xiamen University, Xiamen 361005, China 3 The Third Institute of Oceanography State Oceanic Administration, Xiamen 361005, China
* Author to whom correspondence should be addressed.
Received: 26 October 2008 / Revised: 13 January 2009 / Accepted: 15 January 2009 / Published: 16 January 2009
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Abstract

A new atisane-type diterpene, ent-16α-hydroxy-atisane-3,4-lactone (4) and three known diterpenes, ent-16α-hydroxy-atisane-3-one (1), ent-atisane-3β,16α-diol (2), ent-3,4-seco-16α-hydroxyatis- 4(19)-en -3-oic acid (3) were isolated from the bark of the mangrove plant Excoecaria agallocha. Their structures and relative stereochemistry were elucidated by means of extensive NMR and MS analysis. Compound 3 exhibited significant anti-microfouling activity against the adherence of Pseudomonas pseudoalcaligenes, with an EC50 value of 0.54 ± 0.01 ppm.
Keywords: Diterpenes; Biofilm; Excoecaria agallocha; Anti-microfouling Diterpenes; Biofilm; Excoecaria agallocha; Anti-microfouling
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Wang, Z.C.; Lin, Y.M.; Feng, D.Q.; Ke, C.H.; Lin, P.; Yan, C.L.; Chen, J.D. A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha. Molecules 2009, 14, 414-422.

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