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Molecules 2009, 14(1), 36-45; doi:10.3390/molecules14010036
Article

Caffeic Acid Derivatives from Eupatorium perfoliatum L.

,  and *
University of Münster, Institute for Pharmaceutical Biology and Phytochemistry (IPBP), Hittorfstraße 56, D-48149 Münster, Germany
* Author to whom correspondence should be addressed.
Received: 25 November 2008 / Revised: 16 December 2008 / Accepted: 18 December 2008 / Published: 23 December 2008
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Abstract

From the ethyl acetate soluble fraction of a methanol/water extract of the herb Eupatorium perfoliatum L. (Asteraceae) six caffeic acid derivatives have been isolated and identified by 1D- and 2D-NMR spectroscopic data. Besides the common quinic acid derivatives 5-caffeoylquinic acid (chlorogenic acid), 3-caffeoylquinic acid (neochlorogenic acid) and 3,5-dicaffeoylquinic acid, three up to now unknown depsides of caffeic acid with glucaric acid have been isolated: 2,5-dicaffeoylglucaric acid, 3,4-dicaffeoylglucaric acid, and 2,4- or 3,5-dicaffeoylglucaric acid.
Keywords: Eupatorium perfoliatum L.; Asteraceae; Flavonoids; Dicaffeoylglucaric acid; NMR Eupatorium perfoliatum L.; Asteraceae; Flavonoids; Dicaffeoylglucaric acid; NMR
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Maas, M.; Petereit, F.; Hensel, A. Caffeic Acid Derivatives from Eupatorium perfoliatum L.. Molecules 2009, 14, 36-45.

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