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Molecules 2009, 14(1), 36-45; doi:10.3390/molecules14010036

Caffeic Acid Derivatives from Eupatorium perfoliatum L.

,  and *
University of Münster, Institute for Pharmaceutical Biology and Phytochemistry (IPBP), Hittorfstraße 56, D-48149 Münster, Germany
* Author to whom correspondence should be addressed.
Received: 25 November 2008 / Revised: 16 December 2008 / Accepted: 18 December 2008 / Published: 23 December 2008
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From the ethyl acetate soluble fraction of a methanol/water extract of the herb Eupatorium perfoliatum L. (Asteraceae) six caffeic acid derivatives have been isolated and identified by 1D- and 2D-NMR spectroscopic data. Besides the common quinic acid derivatives 5-caffeoylquinic acid (chlorogenic acid), 3-caffeoylquinic acid (neochlorogenic acid) and 3,5-dicaffeoylquinic acid, three up to now unknown depsides of caffeic acid with glucaric acid have been isolated: 2,5-dicaffeoylglucaric acid, 3,4-dicaffeoylglucaric acid, and 2,4- or 3,5-dicaffeoylglucaric acid.
Keywords: Eupatorium perfoliatum L.; Asteraceae; Flavonoids; Dicaffeoylglucaric acid; NMR Eupatorium perfoliatum L.; Asteraceae; Flavonoids; Dicaffeoylglucaric acid; NMR
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Maas, M.; Petereit, F.; Hensel, A. Caffeic Acid Derivatives from Eupatorium perfoliatum L.. Molecules 2009, 14, 36-45.

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