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Caffeic Acid Derivatives from Eupatorium perfoliatum L.
University of Münster, Institute for Pharmaceutical Biology and Phytochemistry (IPBP), Hittorfstraße 56, D-48149 Münster, Germany
* Author to whom correspondence should be addressed.
Received: 25 November 2008; in revised form: 16 December 2008 / Accepted: 18 December 2008 / Published: 23 December 2008
Abstract: From the ethyl acetate soluble fraction of a methanol/water extract of the herb Eupatorium perfoliatum L. (Asteraceae) six caffeic acid derivatives have been isolated and identified by 1D- and 2D-NMR spectroscopic data. Besides the common quinic acid derivatives 5-caffeoylquinic acid (chlorogenic acid), 3-caffeoylquinic acid (neochlorogenic acid) and 3,5-dicaffeoylquinic acid, three up to now unknown depsides of caffeic acid with glucaric acid have been isolated: 2,5-dicaffeoylglucaric acid, 3,4-dicaffeoylglucaric acid, and 2,4- or 3,5-dicaffeoylglucaric acid.
Keywords: Eupatorium perfoliatum L.; Asteraceae; Flavonoids; Dicaffeoylglucaric acid; NMR
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Maas, M.; Petereit, F.; Hensel, A. Caffeic Acid Derivatives from Eupatorium perfoliatum L.. Molecules 2009, 14, 36-45.
Maas M, Petereit F, Hensel A. Caffeic Acid Derivatives from Eupatorium perfoliatum L.. Molecules. 2009; 14(1):36-45.
Maas, Mareike; Petereit, Frank; Hensel, Andreas. 2009. "Caffeic Acid Derivatives from Eupatorium perfoliatum L.." Molecules 14, no. 1: 36-45.