Next Article in Journal
A Simple, Rapid and Mild One Pot Synthesis of Benzene Ring Acylated and Demethylated Analogues of Harmine under Solvent-free Conditions
Previous Article in Journal
5-Fluorouracil: Mechanisms of Resistance and Reversal Strategies
Molecules 2008, 13(8), 1570-1583; doi:10.3390/molecules13081570
Article

4-Azatricyclo[5.2.2.02,6]undecane-3,5,8-triones as Potential Pharmacological Agents

1, 1, 2, 2, 2 and 1,*
1 Department of Medical Chemistry, The Medical University of Warsaw, 3 Oczki Street, 02-007 Warsaw, Poland 2 Faculty of Chemistry, Maria Curie-Sklodowska University, 20-031 Lublin, Poland
* Author to whom correspondence should be addressed.
Received: 14 May 2008 / Revised: 19 June 2008 / Accepted: 25 July 2008 / Published: 6 August 2008
View Full-Text   |   Download PDF [297 KB, uploaded 18 June 2014]   |   Browse Figures
SciFeed

Abstract

A series of twenty six arylpiperazine and aminoalkanol derivatives of 4-azatricyclo[ 5.2.2.02,6]undecane-3,5,8-trione have been prepared. The synthesized compounds were evaluated for their cytotoxicity and anti-HIV-1 activity in MT-4 cells.
Keywords: 4-Azatricyclo[5.2.2.02; 6]undecane-3; 5; 8-trione; arylpiperazine derivatives; crystal structure; anti-HIV-1 activity 4-Azatricyclo[5.2.2.02; 6]undecane-3; 5; 8-trione; arylpiperazine derivatives; crystal structure; anti-HIV-1 activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Kossakowski, J.; Bielenica, A.; Mirosław, B.; Kozioł, A.E.; Dybała, I.; Struga, M. 4-Azatricyclo[5.2.2.02,6]undecane-3,5,8-triones as Potential Pharmacological Agents. Molecules 2008, 13, 1570-1583.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert