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Molecules 2008, 13(4), 977-985; doi:10.3390/molecules13040977
Article

Microwave-Enhanced Sulphated Zirconia and SZ/MCM-41 Catalyzed Regioselective Synthesis of β-Amino Alcohols Under Solvent-Free Conditions

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Received: 8 April 2008 / Revised: 24 April 2007 / Accepted: 24 April 2008 / Published: 26 April 2008
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Abstract

A solvent-free approach for the regioselective synthesis of β-amino alcohols inshorter reaction times and higher yields, compared to conventional heating is described. Itinvolves microwave (MW) exposure of undiluted reactants in the presence of sulphatedzirconia (SZ) or sulphated zirconia over MCM-41 (SZM) as catalyst. Both acid materialscan be easily recovered and reused.
Keywords: Sulphated zirconia; amino alcohols; microwaves; regioselective; oxiranes. Sulphated zirconia; amino alcohols; microwaves; regioselective; oxiranes.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Negrón-Silva, G.; Hernández-Reyes, C.X.; Angeles-Beltrán, D.; Lomas-Romero, L.; González-Zamora, E. Microwave-Enhanced Sulphated Zirconia and SZ/MCM-41 Catalyzed Regioselective Synthesis of β-Amino Alcohols Under Solvent-Free Conditions. Molecules 2008, 13, 977-985.

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