Next Article in Journal
Two New Constituents from Artemisia capillaris Thunb.
Previous Article in Journal
Cholesterylbutyrate Solid Lipid Nanoparticles as a Butyric Acid Prodrug
Molecules 2008, 13(2), 255-266; doi:10.3390/molecules13020255

New Benzoyl Glucosides and Cytotoxic Pterosin Sesquiterpenes from Pteris ensiformis Burm.

1 Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan 2 Department of Biotechnology, Chia-Nan University of Pharmacy and Science, Tainan 717, Taiwan
* Author to whom correspondence should be addressed.
Received: 18 January 2008 / Revised: 4 February 2008 / Accepted: 4 February 2008 / Published: 5 February 2008
Download PDF [96 KB, uploaded 18 June 2014]


Three new compounds: 2R,3R-pterosin L 3-O-β-D-glucopyranoside (1), β-Dxylopyranosyl(1→2)-7-O-benzoyl-β-D-glucopyranoside (2) and 4-O-benzoyl-β-D-xylopyranosyl(1→2)-7-O-benzoyl-β-D-glucopyranoside (3), together with nine knowncompounds, were isolated from the ethyl acetate extract of Pteris ensiformis. 5-[2-Hydroxyethylidene]-2(5H)-furanone (4), which had been synthesized, was isolated fromnatural sources for the first time. The structures of all isolated compounds were determinedon the basis of mass and spectroscopic evidence. Compound 1 and pterosin B (5) showcytotoxicity against HL 60 cells (human leukemia) with the IC50 values of 3.7 and 8.7μg/mL, respectively.
Keywords: Pteris ensiformis; pterosin B; human leukemia Pteris ensiformis; pterosin B; human leukemia
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
MDPI and ACS Style

Chen, Y.-H.; Chang, F.-R.; Lu, M.-C.; Hsieh, P.-W.; Wu, M.-J.; Du, Y.-C.; Wu, Y.-C. New Benzoyl Glucosides and Cytotoxic Pterosin Sesquiterpenes from Pteris ensiformis Burm.. Molecules 2008, 13, 255-266.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


Cited By

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert