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Molecules 2008, 13(2), 212-219; doi:10.3390/molecules13020212
Communication

Antifouling Metabolites from the Mangrove Plant Ceriops tagal

1, 2, 1, 1, 3 and 1,*
1 Department of Biology, School of Life Sciences, Xiamen University, Xiamen 361005, P.R. China 2 College of Oceanography and Environmental Science, Xiamen University, Xiamen 361005, P.R. China 3 Pharmaceutical Department, Medical School, Xiamen University, Xiamen 361005, P. R. China
* Author to whom correspondence should be addressed.
Received: 28 November 2007 / Revised: 29 January 2008 / Accepted: 29 January 2008 / Published: 31 January 2008
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Abstract

The new diterpene methoxy-ent-8(14)-pimarenely-15-one (1) and three knownmetabolites: ent-8(14)-pimarene-15R,16-diol (2), stigmasterol (3) and β-sitosterol (4), wereisolated from the roots of the mangrove plant Ceriops tagal. Their structures and relativestereochemistry were elucidated by means of extensive NMR, IR and MS analysis.Compounds 1, 2, 3 and 4 exhibited significant antifouling activities against cyprid larvaeof the barnacle Balanus albicostatus Pilsbry, with EC50 values of 0.32 ± 0.01, 0.04 ± 0.00,4.05 ± 0.15 and 18.47 ± 0.40 μg/cm2, respectively, whereas their toxicities towards cypridswere very low, with LC50 values all above 10 μg/cm2.
Keywords: Diterpenes; antifouling activity; barnacle; Ceriops tagal Diterpenes; antifouling activity; barnacle; Ceriops tagal
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Chen, J.D.; Feng, D.Q.; Yang, Z.W.; Wang, Z.C.; Qiu, Y.; Lin, Y.M. Antifouling Metabolites from the Mangrove Plant Ceriops tagal. Molecules 2008, 13, 212-219.

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