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Antifouling Metabolites from the Mangrove Plant Ceriops tagal
Department of Biology, School of Life Sciences, Xiamen University, Xiamen 361005, P.R. China
College of Oceanography and Environmental Science, Xiamen University, Xiamen 361005, P.R. China
Pharmaceutical Department, Medical School, Xiamen University, Xiamen 361005, P. R. China
* Author to whom correspondence should be addressed.
Received: 28 November 2007; in revised form: 29 January 2008 / Accepted: 29 January 2008 / Published: 31 January 2008
Abstract: The new diterpene methoxy-ent-8(14)-pimarenely-15-one (1) and three knownmetabolites: ent-8(14)-pimarene-15R,16-diol (2), stigmasterol (3) and β-sitosterol (4), wereisolated from the roots of the mangrove plant Ceriops tagal. Their structures and relativestereochemistry were elucidated by means of extensive NMR, IR and MS analysis.Compounds 1, 2, 3 and 4 exhibited significant antifouling activities against cyprid larvaeof the barnacle Balanus albicostatus Pilsbry, with EC50 values of 0.32 ± 0.01, 0.04 ± 0.00,4.05 ± 0.15 and 18.47 ± 0.40 μg/cm2, respectively, whereas their toxicities towards cypridswere very low, with LC50 values all above 10 μg/cm2.
Keywords: Diterpenes; antifouling activity; barnacle; Ceriops tagal
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Chen, J.D.; Feng, D.Q.; Yang, Z.W.; Wang, Z.C.; Qiu, Y.; Lin, Y.M. Antifouling Metabolites from the Mangrove Plant Ceriops tagal. Molecules 2008, 13, 212-219.
Chen JD, Feng DQ, Yang ZW, Wang ZC, Qiu Y, Lin YM. Antifouling Metabolites from the Mangrove Plant Ceriops tagal. Molecules. 2008; 13(2):212-219.
Chen, Jun D.; Feng, Dan Q.; Yang, Zhi W.; Wang, Zhan C.; Qiu, Yan; Lin, Yi M. 2008. "Antifouling Metabolites from the Mangrove Plant Ceriops tagal." Molecules 13, no. 2: 212-219.