Molecules 2008, 13(12), 2962-2974; doi:10.3390/molecules13122962
Article

Enantioselective Synthesis of Homo-N-Nucleosides Containing a 1,4-Dioxane Sugar Analog

email and * email
Received: 3 September 2008; in revised form: 30 October 2008 / Accepted: 7 November 2008 / Published: 3 December 2008
(This article belongs to the Special Issue Nucleic Acids)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A dioxane homo-sugar analog, (2S,5S)-and (2R,5S)-5-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-iodomethyl-1,4-dioxane was prepared from (2R,3R)-dimethyl tartrate, and further elaborated into the corresponding homo-N-nucleoside analogs by its reactions with uracil and adenine, respectively.
Keywords: Sugar analog; Nucleoside analogs; Homo-N-Nucleoside; 1; 4-Dioxane; Hetero-cycles
PDF Full-text Download PDF Full-Text [301 KB, uploaded 18 June 2014 19:28 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Yu, Q.; Carlsen, P. Enantioselective Synthesis of Homo-N-Nucleosides Containing a 1,4-Dioxane Sugar Analog. Molecules 2008, 13, 2962-2974.

AMA Style

Yu Q, Carlsen P. Enantioselective Synthesis of Homo-N-Nucleosides Containing a 1,4-Dioxane Sugar Analog. Molecules. 2008; 13(12):2962-2974.

Chicago/Turabian Style

Yu, Qiang; Carlsen, Per. 2008. "Enantioselective Synthesis of Homo-N-Nucleosides Containing a 1,4-Dioxane Sugar Analog." Molecules 13, no. 12: 2962-2974.


Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert