Molecules 2008, 13(11), 2796-2803; doi:10.3390/molecules13112796
Article

A New Phloroglucinol Diglycoside Derivative from Hypericum japonicum Thunb.

Xiao Wei Wang 1,2 email, Yu Mao 2 email, Nai-Li Wang 1,* email and Xin Sheng Yao 1,* email
1 Department of Natural Products Chemistry, Shenyang Pharmaceutical University, 103. Wenhua Road Shenhe District, Shenyang, Liaoning 110016, P.R. China 2 Shenzhen Institute for Drug Control, Shenzhen, Guangdong 518029, P.R. China
* Authors to whom correspondence should be addressed.
Received: 30 September 2008; in revised form: 27 October 2008 / Accepted: 4 November 2008 / Published: 7 November 2008
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Abstract: A new phloroglucinol diglycoside 1, together with eight known compounds, were isolated from Hypericum japonicum Thunb. The structure of the new compound 1 was determined by spectroscopic methods to be 4,6-dimethyl-5-O-[α-L-rhamnopyranosyl-(1→6)-α-D-glucopyranosyl] multifidol. Different solvent extracts of Hypericum japonicum Thunb. were tested for in vivo antihypoxic activity using mice, with the EtOAc extract showing better activity.
Keywords: Hypericum japonicum Thunb.; 4; 6-Dimethyl-5-O-[á-L-rhamnopyranosyl- (1→6)-â-D-Glucopyranosyl] multifidol; Antihypoxic activity

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Cite This Article

MDPI and ACS Style

Wang, X.W.; Mao, Y.; Wang, N.-L.; Yao, X.S. A New Phloroglucinol Diglycoside Derivative from Hypericum japonicum Thunb.. Molecules 2008, 13, 2796-2803.

AMA Style

Wang XW, Mao Y, Wang N-L, Yao XS. A New Phloroglucinol Diglycoside Derivative from Hypericum japonicum Thunb.. Molecules. 2008; 13(11):2796-2803.

Chicago/Turabian Style

Wang, Xiao W.; Mao, Yu; Wang, Nai-Li; Yao, Xin S. 2008. "A New Phloroglucinol Diglycoside Derivative from Hypericum japonicum Thunb.." Molecules 13, no. 11: 2796-2803.

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