This article is
- freely available
Norcyperone, a Novel Skeleton Norsesquiterpene from Cyperus rotundus L.
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, P. R. China
College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, P. R. China
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P. R. China
* Authors to whom correspondence should be addressed.
Received: 21 August 2008; in revised form: 25 September 2008 / Accepted: 26 September 2008 / Published: 10 October 2008
Abstract: A novel norsesquiterpene, named norcyperone (1), and three known compounds: (-)-clovane-2,9-diol (2), rosenonolactone (3), and 5a,8a-epidioxy-(20S,22E,24R)-ergosta-6,22-dien-3β-ol (4) were isolated from the rhizomes of Cyperus rotundus L. The structure of 1 was elucidated as 8,11,11-trimethylbicyclo[5.3.1]undecane-5a, 8a-epoxy-3-one on the basis of extensive spectroscopic analyses, including 1D- and 2D-NMR, MS experiments, and single-crystal X-ray diffraction. This is the first report of a 8,11,11-trimethyl- bicyclo[5.3.1]undecane-3-one type norsesquiterpene with a tetrahydrofuran ring at C-5 and C-8.
Keywords: Cyperus rotundus L.; norsesquiterpene; norcyperone; bicyclo[5.3.1]undecane-3-one
Article StatisticsClick here to load and display the download statistics.
Notes: Multiple requests from the same IP address are counted as one view.
Cite This Article
MDPI and ACS Style
Xu, Y.; Zhang, H.-W.; Yu, C.-Y.; Lu, Y.; Chang, Y.; Zou, Z.-M. Norcyperone, a Novel Skeleton Norsesquiterpene from Cyperus rotundus L.. Molecules 2008, 13, 2474-2481.
Xu Y, Zhang H-W, Yu C-Y, Lu Y, Chang Y, Zou Z-M. Norcyperone, a Novel Skeleton Norsesquiterpene from Cyperus rotundus L.. Molecules. 2008; 13(10):2474-2481.
Xu, Yan; Zhang, Hong-Wu; Yu, Chang-Yuan; Lu, Yang; Chang, Ying; Zou, Zhong-Mei. 2008. "Norcyperone, a Novel Skeleton Norsesquiterpene from Cyperus rotundus L.." Molecules 13, no. 10: 2474-2481.