Next Article in Journal
Synthesis of Jasmonoides from Furan Derivatives
Previous Article in Journal
Synthesis Of Some Novel Silver-Cysteamine Complexes
Molecules 2008, 13(10), 2474-2481; doi:10.3390/molecules13102474
Article

Norcyperone, a Novel Skeleton Norsesquiterpene from Cyperus rotundus L.

1, 1, 2,* , 3, 3 and 1,*
1 Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, P. R. China 2 College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, P. R. China 3 Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P. R. China
* Authors to whom correspondence should be addressed.
Received: 21 August 2008 / Revised: 25 September 2008 / Accepted: 26 September 2008 / Published: 10 October 2008
Download PDF [243 KB, uploaded 18 June 2014]

Abstract

A novel norsesquiterpene, named norcyperone (1), and three known compounds: (-)-clovane-2,9-diol (2), rosenonolactone (3), and 5a,8a-epidioxy-(20S,22E,24R)-ergosta-6,22-dien-3β-ol (4) were isolated from the rhizomes of Cyperus rotundus L. The structure of 1 was elucidated as 8,11,11-trimethylbicyclo[5.3.1]undecane-5a, 8a-epoxy-3-one on the basis of extensive spectroscopic analyses, including 1D- and 2D-NMR, MS experiments, and single-crystal X-ray diffraction. This is the first report of a 8,11,11-trimethyl- bicyclo[5.3.1]undecane-3-one type norsesquiterpene with a tetrahydrofuran ring at C-5 and C-8.
Keywords: Cyperus rotundus L.; norsesquiterpene; norcyperone; bicyclo[5.3.1]undecane-3-one Cyperus rotundus L.; norsesquiterpene; norcyperone; bicyclo[5.3.1]undecane-3-one
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Export to BibTeX |
EndNote


MDPI and ACS Style

Xu, Y.; Zhang, H.-W.; Yu, C.-Y.; Lu, Y.; Chang, Y.; Zou, Z.-M. Norcyperone, a Novel Skeleton Norsesquiterpene from Cyperus rotundus L.. Molecules 2008, 13, 2474-2481.

View more citation formats

Related Articles

Article Metrics

Comments

Citing Articles

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert