Next Article in Journal / Special Issue
Radiation- and Photo-induced Activation of 5-Fluorouracil Prodrugs as a Strategy for the Selective Treatment of Solid Tumors
Previous Article in Journal
2-Arylhydrazonopropanals as Building Blocks in Heterocyclic Chemistry: Microwave Assisted Condensation of 2-Arylhydrazonopropanals with Amines and Active Methylene Reagents
Previous Article in Special Issue
Efficacy of the Oral Fluorouracil Pro-drug Capecitabine in Cancer Treatment: a Review
Molecules 2008, 13(10), 2340-2369; doi:10.3390/molecules13102340
Review

Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems

Received: 22 April 2008 / Revised: 16 September 2008 / Accepted: 16 September 2008 / Published: 1 October 2008
(This article belongs to the Special Issue 5-Fluorouracil)
Download PDF [717 KB, uploaded 18 June 2014]

Abstract

Because of the fundamental importance of new therapeutic routes for cancer treatment, a number of systems based on colloidal particles as vehicles for the delivery of the anticancer drug 5-fluorouracil have been devised. The target is always to provide the proper dose of the antitumor agent only at the desired locus of action, thus reducing the unwanted side effects. In this review, the main strategies and the more significant results in the development of 5-fluorouracil carriers for cancer treatment are discussed.
Keywords: Biodegradable polymers; Cancer treatment; Drug carriers; 5-Fluorouracil; Vesicular systems Biodegradable polymers; Cancer treatment; Drug carriers; 5-Fluorouracil; Vesicular systems
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Arias, J.L. Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems. Molecules 2008, 13, 2340-2369.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

Cited By

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert