Molecules 2008, 13(10), 2340-2369; doi:10.3390/molecules13102340
Review

Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems

Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Granada, Campus Universitario de Cartuja s/n, 18071 Granada, Spain
Received: 22 April 2008; in revised form: 16 September 2008 / Accepted: 16 September 2008 / Published: 1 October 2008
(This article belongs to the Special Issue 5-Fluorouracil)
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Abstract: Because of the fundamental importance of new therapeutic routes for cancer treatment, a number of systems based on colloidal particles as vehicles for the delivery of the anticancer drug 5-fluorouracil have been devised. The target is always to provide the proper dose of the antitumor agent only at the desired locus of action, thus reducing the unwanted side effects. In this review, the main strategies and the more significant results in the development of 5-fluorouracil carriers for cancer treatment are discussed.
Keywords: Biodegradable polymers; Cancer treatment; Drug carriers; 5-Fluorouracil; Vesicular systems

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MDPI and ACS Style

Arias, J.L. Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems. Molecules 2008, 13, 2340-2369.

AMA Style

Arias JL. Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems. Molecules. 2008; 13(10):2340-2369.

Chicago/Turabian Style

Arias, José L. 2008. "Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems." Molecules 13, no. 10: 2340-2369.

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