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Molecules 2008, 13(1), 157-169; doi:10.3390/molecules13010157

The Synthesis of Unsubstituted Cyclic Imides Using Hydroxylamine under Microwave Irradiation

1,*  and 2
1 Department of Chemistry and Physics, Arkansas State University, State University, AR 72467, USA 2 Department of Chemistry, Morgan State University, Baltimore, MD 21251, USA
* Author to whom correspondence should be addressed.
Received: 26 December 2007 / Revised: 21 January 2008 / Accepted: 22 January 2008 / Published: 25 January 2008
(This article belongs to the Special Issue ECSOC-11)
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Unsubstituted cyclic imides were synthesized from a series of cyclic anhydrides,hydroxylamine hydrochloride (NH2OH·HCl), and 4-N,N-dimethylamino-pyridine (DMAP,base catalyst) under microwave irradiation in monomode and multimode microwaves. Thisnovel microwave synthesis produced high yields of the unsubstituted cyclic imides forboth the monomode (61 - 81%) and multimode (84 - 97%) microwaves.
Keywords: Hydroxylamine·HCl; unsubstituted cyclic imides; DMAP; microwaves. Hydroxylamine·HCl; unsubstituted cyclic imides; DMAP; microwaves.
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Benjamin, E.; Hijji, Y. The Synthesis of Unsubstituted Cyclic Imides Using Hydroxylamine under Microwave Irradiation. Molecules 2008, 13, 157-169.

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