Next Article in Journal
Full Open Access Publishing Policy Imposed in 2007: Molecules Publishes Many More Papers This Year – More than 2000 Pages Published up to Issue 8
Next Article in Special Issue
Bile Acid Scaffolds in Supramolecular Chemistry: The Interplay of Design and Synthesis
Previous Article in Journal
Targeted Synthesis of 1-(4-Hydroxyiminomethylpyridinium)-3-pyridiniumpropane Dibromide – A New Nerve Agent Reactivator
Previous Article in Special Issue
Synthesis of Novel Steroid-Peptoid Hybrid Macrocycles by Multiple Multicomponent Macrocyclizations Including Bifunctional Building Blocks (MiBs)
Article Menu

Article Versions

Export Article

Open AccessReview
Molecules 2007, 12(8), 1973-2000; doi:10.3390/12081973

Supramolecular Chirality in Crystalline Assemblies of Bile Acids and Their Derivatives; Three-Axial, Tilt, Helical, and Bundle Chirality

Department of Material and Life Science, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan
*
Author to whom correspondence should be addressed.
Received: 30 June 2007 / Revised: 20 August 2007 / Accepted: 20 August 2007 / Published: 22 August 2007
(This article belongs to the Special Issue Bile Acids)

Abstract

Steroidal bile acids and their derivatives exhibit characteristic inclusion behaviors in the crystalline state. Their crystals present varied assemblies due to asymmetric molecular structures, which relate to supramolecular properties through cooperative weak interactions. An overview indicates that the steroidal assemblies lie in an intermediate position among various molecules and have hierarchical structures such as primary, secondary, tertiary, and host-guest assemblies like proteins. Such an interpretation brought about the idea that the assemblies with dimensionality present supramolecular chirality such as three-axial, tilt, helical, bundle, and complementary chirality. This concept of the supramolecular chirality enables us to understand formation of chiral crystals starting from the molecular chirality of the steroidal molecules. View Full-Text
Keywords: Steroidal bile acids; inclusion crystal; supramolecular chirality; helices; molecular tilt Steroidal bile acids; inclusion crystal; supramolecular chirality; helices; molecular tilt
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Miyata, M.; Tohnai, N.; Hisaki, I. Supramolecular Chirality in Crystalline Assemblies of Bile Acids and Their Derivatives; Three-Axial, Tilt, Helical, and Bundle Chirality. Molecules 2007, 12, 1973-2000.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top