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Molecules 2007, 12(8), 1632-1640; doi:10.3390/12081632
Article

Novel and Efficient Synthesis of N,N-Dialkylaminoand O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) Phosphonohydrazido Oximes - Potential Marine Fish Toxin Analogues. Part 2

,  and *
Process Technology Development Division, Defence R and D Establishment, Jhansi Road, Gwalior- 474002 (MP), India
* Author to whom correspondence should be addressed.
Received: 6 July 2007 / Revised: 26 July 2007 / Accepted: 26 July 2007 / Published: 2 August 2007
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Abstract

A novel and efficient method for the synthesis of N,N-dialkylamino/O-alkyl phenyl-2-(1-alkyl/phenyl-2-oxopropylidene) phosphonohydrazido oximes 4 using activated silica has been developed. The reaction involves the condensation of substituted α- ketooxime and N,N-dialkylaminophenylphosphonohydrazides or O-alkylphenylphosphonohydrazides and gave the corresponding phosphonohydrazido oximes in excellent yields under mild conditions.
Keywords: Hydrazides; α-ketooxime; marine fish toxin; phosphonohydrazido oximes;phenyl derivatives. Hydrazides; α-ketooxime; marine fish toxin; phosphonohydrazido oximes; phenyl derivatives.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Kumar, R.; Gupta, A.K.; Kaushik, M.P. Novel and Efficient Synthesis of N,N-Dialkylaminoand O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) Phosphonohydrazido Oximes - Potential Marine Fish Toxin Analogues. Part 2. Molecules 2007, 12, 1632-1640.

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