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Molecules 2007, 12(8), 1596-1605; doi:10.3390/12081596

Synthesis and Biological Activity of Some Novel Derivatives of 4-Amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole

1
College of Education, Wenzhou University, Wenzhou 325035, P.R. China
2
College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325027, P.R.China
*
Author to whom correspondence should be addressed.
Received: 30 May 2007 / Revised: 25 July 2007 / Accepted: 25 July 2007 / Published: 27 July 2007
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Abstract

To discover new 1,2,4-triazole derivatives which may possess significant biological activities, we synthesized a series of novel 6-aryl-3-(D-galactopentitol-1-yl)- 7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines and 4-(arylmethylidene)amino-5-(D-galactopentitol- 1-yl)-3-mercapto-4H-1,2,4-triazoles from 4-amino-3-(D-galactopentitol-1-yl)-5- mercapto-1,2,4-triazole. All the title compounds were characterized by elemental analysis, IR, 1H- and 13C-NMR. Plant growth-regulating activity tests showed that these compounds have remarkable effects on the growth of radish and wheat.
Keywords: Galactose; 1; 2; 4-triazolo[3; 4-b]-1; 3; 4-thiadiazine; 4-(arylmethylidene)amino-5-(D-galactopentitol-1-yl)-3-mercapto-4H-1; 2; 4-triazole; NMR; plant growth-regulating. Galactose; 1; 2; 4-triazolo[3; 4-b]-1; 3; 4-thiadiazine; 4-(arylmethylidene)amino-5-(D-galactopentitol-1-yl)-3-mercapto-4H-1; 2; 4-triazole; NMR; plant growth-regulating.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Jin, J.-Y.; Zhang, L.-X.; Zhang, A.-J.; Lei, X.-X.; Zhu, J.-H. Synthesis and Biological Activity of Some Novel Derivatives of 4-Amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole. Molecules 2007, 12, 1596-1605.

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