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Molecules 2007, 12(7), 1420-1429; doi:10.3390/12071420
Article

An Efficient and Rapid Synthetic Route to Biologically Interesting Pyranochalcone Natural Products

* ,  and
School of Chemical Engineering and Technology, Yeungnam University, Gyeongsan 712-749, Korea
* Author to whom correspondence should be addressed.
Received: 29 June 2007 / Revised: 10 July 2007 / Accepted: 10 July 2007 / Published: 12 July 2007
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Abstract

An efficient and concise total synthesis of naturally occurring pyranochalcones was achieved from readily available 2,4-dihydroxyacetophenone and 2,4-dihydroxy-6- methoxyacetophenone. The key steps in the synthetic strategy were ethylenediamine diacetate-catalyzed benzopyran formation and aldol reactions.
Keywords: Ethylenediamine diacetate;Pyranyl ring formation;Pyranochalcone natural products;Aldol reaction Ethylenediamine diacetate; Pyranyl ring formation; Pyranochalcone natural products; Aldol reaction
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Lee, Y.R.; Wang, X.; Xia, L. An Efficient and Rapid Synthetic Route to Biologically Interesting Pyranochalcone Natural Products. Molecules 2007, 12, 1420-1429.

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