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Molecules 2007, 12(6), 1202-1209; https://doi.org/10.3390/12061202

Synthesis and Biological Evaluation of Some Novel Schiff’s Bases from 1,2,4-Triazole

1
College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325027, P .R. China
2
Wenzhou Medical College, Wenzhou 325035, P. R. China
*
Author to whom correspondence should be addressed.
Received: 7 April 2007 / Revised: 3 June 2007 / Accepted: 4 June 2007 / Published: 5 July 2007
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Abstract

We have synthesized a number of novel Schiff’s bases from 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1,2,4-triazole-5-thione. By attaching D-glucoheptonic-hexitol-1-yl residues to 1,2,4-triazole at the 3-position, the solubility of the title compounds has been improved greatly. All the products have been characterized by elemental analysis, IR, 1H-NMR, 13C-NMR and MS. The plant-growth regulating effects of the title compounds were examined. From the biological activity results, we found that most compounds showed weak to moderate activities. View Full-Text
Keywords: Schiff's bases; glucoheptonic acid residue; 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1; 2; 4-triazole-5-thione; plant growth regulation Schiff's bases; glucoheptonic acid residue; 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1; 2; 4-triazole-5-thione; plant growth regulation
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Ye, X.-X.; Chen, Z.-F.; Zhang, A.-J.; Zhang, L.-X. Synthesis and Biological Evaluation of Some Novel Schiff’s Bases from 1,2,4-Triazole. Molecules 2007, 12, 1202-1209.

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