Next Article in Journal
Synthesis and Fluorescence Properties of 5,7-Diphenylquinoline and 2,5,7-Triphenylquinoline Derived from m-Terphenylamine
Previous Article in Journal
A New Type of NADH Model Compound: Synthesis and Enantioselective Reduction of Benzoylformates to the Corresponding Mandelates
Molecules 2007, 12(6), 1202-1209; doi:10.3390/12061202
Article

Synthesis and Biological Evaluation of Some Novel Schiff’s Bases from 1,2,4-Triazole

1
,
1, 1
 and
1,*
1 College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325027, P .R. China 2 Wenzhou Medical College, Wenzhou 325035, P. R. China
* Author to whom correspondence should be addressed.
Received: 7 April 2007 / Revised: 3 June 2007 / Accepted: 4 June 2007 / Published: 5 July 2007
View Full-Text   |   Download PDF [200 KB, uploaded 18 June 2014]   |  

Abstract

We have synthesized a number of novel Schiff’s bases from 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1,2,4-triazole-5-thione. By attaching D-glucoheptonic-hexitol-1-yl residues to 1,2,4-triazole at the 3-position, the solubility of the title compounds has been improved greatly. All the products have been characterized by elemental analysis, IR, 1H-NMR, 13C-NMR and MS. The plant-growth regulating effects of the title compounds were examined. From the biological activity results, we found that most compounds showed weak to moderate activities.
Keywords: Schiff's bases; glucoheptonic acid residue; 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1; 2; 4-triazole-5-thione; plant growth regulation Schiff's bases; glucoheptonic acid residue; 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1; 2; 4-triazole-5-thione; plant growth regulation
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
SciFeed

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Ye, X.-X.; Chen, Z.-F.; Zhang, A.-J.; Zhang, L.-X. Synthesis and Biological Evaluation of Some Novel Schiff’s Bases from 1,2,4-Triazole. Molecules 2007, 12, 1202-1209.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert