Next Article in Journal
Synthesis and Fluorescence Properties of 5,7-Diphenylquinoline and 2,5,7-Triphenylquinoline Derived from m-Terphenylamine
Previous Article in Journal
A New Type of NADH Model Compound: Synthesis and Enantioselective Reduction of Benzoylformates to the Corresponding Mandelates
Molecules 2007, 12(6), 1202-1209; doi:10.3390/12061202
Article

Synthesis and Biological Evaluation of Some Novel Schiff’s Bases from 1,2,4-Triazole

1
,
1, 1
 and
1,*
Received: 7 April 2007 / Revised: 3 June 2007 / Accepted: 4 June 2007 / Published: 5 July 2007
Download PDF [200 KB, uploaded 18 June 2014]

Abstract

We have synthesized a number of novel Schiff’s bases from 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1,2,4-triazole-5-thione. By attaching D-glucoheptonic-hexitol-1-yl residues to 1,2,4-triazole at the 3-position, the solubility of the title compounds has been improved greatly. All the products have been characterized by elemental analysis, IR, 1H-NMR, 13C-NMR and MS. The plant-growth regulating effects of the title compounds were examined. From the biological activity results, we found that most compounds showed weak to moderate activities.
Keywords: Schiff's bases; glucoheptonic acid residue; 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1; 2; 4-triazole-5-thione; plant growth regulation Schiff's bases; glucoheptonic acid residue; 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1; 2; 4-triazole-5-thione; plant growth regulation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Ye, X.-X.; Chen, Z.-F.; Zhang, A.-J.; Zhang, L.-X. Synthesis and Biological Evaluation of Some Novel Schiff’s Bases from 1,2,4-Triazole. Molecules 2007, 12, 1202-1209.

View more citation formats

Related Articles

Article Metrics

Comments

Citing Articles

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert