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Molecules 2007, 12(3), 694-702; doi:10.3390/12030694

Fast and Highly Efficient Solid State Oxidation of Thiols

* , ,  and
Department of Chemistry, Yasouj University, Yasouj 75918-74831, P. O. Box-35, Iran
* Author to whom correspondence should be addressed.
Received: 22 January 2007 / Revised: 13 February 2007 / Accepted: 26 February 2007 / Published: 31 March 2007
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A fast and efficient solid state method for the chemoselective room temperature oxidative coupling of thiols to afford their corresponding disulfides using inexpensive and readily available moist sodiumperiodate as the reagent is described. The reaction was applicable to a variety of thiols giving high yields after short reaction times. Comparison of yield/time ratios of this method with some of those reported in the literature shows the superiority of this reagent over others under these conditions.
Keywords: Solid state reaction; oxidation; periodate; thiols; disulfides. Solid state reaction; oxidation; periodate; thiols; disulfides.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Montazerozohori, M.; Joohari, S.; Karami, B.; Haghighat, N. Fast and Highly Efficient Solid State Oxidation of Thiols. Molecules 2007, 12, 694-702.

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