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Synthesis of New L-Ascorbic Ferulic Acid Hybrids
Université de Caen Basse-Normandie, U.F.R. des Sciences Pharmaceutiques, Centre d’Etudes et de Recherche sur le Médicament de Normandie, UPRES EA-3915, 5, rue Vaubénard, 14032 CAEN Cedex, France
* Author to whom correspondence should be addressed.
Received: 30 October 2007; in revised form: 15 November 2007 / Accepted: 15 November 2007 / Published: 17 November 2007
Abstract: A feasibility and chemical study of the coupling conditions of L-ascorbic acidwith ferulic acid derivatives are described on the basis of the known synergistic effects ofmixtures of various antioxidants. Novel L-ascorbic ferulic hybrids linked at the C-3hydroxyl group were prepared with the aim to protect the alcohol function and the enediolsystem.
Keywords: Ascorbic acid; ferulic acid; hybridization; antioxidant; oxidative stress.
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Voisin-Chiret, A.S.; Bazin, M.-A.; Lancelot, J.-C.; Rault, S. Synthesis of New L-Ascorbic Ferulic Acid Hybrids. Molecules 2007, 12, 2533-2545.
Voisin-Chiret AS, Bazin M-A, Lancelot J-C, Rault S. Synthesis of New L-Ascorbic Ferulic Acid Hybrids. Molecules. 2007; 12(11):2533-2545.
Voisin-Chiret, Anne Sophie; Bazin, Marc-Antoine; Lancelot, Jean-Charles; Rault, Sylvain. 2007. "Synthesis of New L-Ascorbic Ferulic Acid Hybrids." Molecules 12, no. 11: 2533-2545.