Microwave-Assisted Synthesis of Substituted Hexahydro-pyrrolo[3,2-c]quinolines

doi:10.3390/12010049

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Molecules 2007, 12(1), 49-59; doi:10.3390/12010049

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Microwave-Assisted Synthesis of Substituted Hexahydro-pyrrolo[3,2-c]quinolines

Michal Neuschl¹, Darek Bogdal² and Milan Potacek^1,*

¹ Department of Organic Chemistry, Masaryk University, Kotlářská 2, 611 37 Brno, Czech Republic ² Faculty of Chemical Engineering and Technology, Politechnika Krakowska, Warszawska 24, 31-155 Krakow, Poland

* Author to whom correspondence should be addressed.

Received: 22 December 2006; in revised form: 15 January 2007 / Accepted: 23 January 2007 / Published: 24 January 2007

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Abstract: New compounds with the ethyl hexahydro-1H-pyrrolo[3,2-c]quinoline-2-carboxylate skeleton were prepared by microwave-assisted intramolecular 1,3-dipolar cycloaddition reactions. The reactions were carried out under solvent-free conditions and compared with the same reaction in the presence of a solvent and a catalyst. Steric effects on the selectivity of the reaction were noted and evaluated.

Keywords: Azomethine ylide;intramolecular 1;3-dipolar cycloaddition;microwave - assisted synthesis;hexahydro-1H-pyrrolo[3;2-c]quinoline.

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MDPI and ACS Style

Neuschl, M.; Bogdal, D.; Potacek, M. Microwave-Assisted Synthesis of Substituted Hexahydro-pyrrolo[3,2-c]quinolines. Molecules 2007, 12, 49-59.

AMA Style

Neuschl M, Bogdal D, Potacek M. Microwave-Assisted Synthesis of Substituted Hexahydro-pyrrolo[3,2-c]quinolines. Molecules. 2007; 12(1):49-59.

Chicago/Turabian Style

Neuschl, Michal; Bogdal, Darek; Potacek, Milan. 2007. "Microwave-Assisted Synthesis of Substituted Hexahydro-pyrrolo[3,2-c]quinolines." Molecules 12, no. 1: 49-59.

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