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Molecules 2007, 12(1), 49-59; doi:10.3390/12010049
Article

Microwave-Assisted Synthesis of Substituted Hexahydro-pyrrolo[3,2-c]quinolines

1, 2
 and
1,*
1 Department of Organic Chemistry, Masaryk University, Kotlářská 2, 611 37 Brno, Czech Republic 2 Faculty of Chemical Engineering and Technology, Politechnika Krakowska, Warszawska 24, 31-155 Krakow, Poland
* Author to whom correspondence should be addressed.
Received: 22 December 2006 / Revised: 15 January 2007 / Accepted: 23 January 2007 / Published: 24 January 2007
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Abstract

New compounds with the ethyl hexahydro-1H-pyrrolo[3,2-c]quinoline-2-carboxylate skeleton were prepared by microwave-assisted intramolecular 1,3-dipolar cycloaddition reactions. The reactions were carried out under solvent-free conditions and compared with the same reaction in the presence of a solvent and a catalyst. Steric effects on the selectivity of the reaction were noted and evaluated.
Keywords: Azomethine ylide;intramolecular 1;3-dipolar cycloaddition;microwave - assisted synthesis;hexahydro-1H-pyrrolo[3;2-c]quinoline. Azomethine ylide; intramolecular 1; 3-dipolar cycloaddition; microwave - assisted synthesis; hexahydro-1H-pyrrolo[3; 2-c]quinoline.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Neuschl, M.; Bogdal, D.; Potacek, M. Microwave-Assisted Synthesis of Substituted Hexahydro-pyrrolo[3,2-c]quinolines. Molecules 2007, 12, 49-59.

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