Application of the Solid-Phase Julia–Lythgoe Olefination in Vitamin D Side-Chain Construction

doi:10.3390/11080655

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Molecules 2006, 11(8), 655-660; doi:10.3390/11080655

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Application of the Solid-Phase Julia–Lythgoe Olefination in Vitamin D Side-Chain Construction

Jo N. D'herde and Pierre J. De Clercq*

Ghent University, Department of Organic Chemistry, Laboratory for Organic Synthesis, Krijgslaan 281 (S4), B-9000 Gent, Belgium

* Author to whom correspondence should be addressed.

Received: 11 August 2006 / Accepted: 22 August 2006 / Published: 26 August 2006

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Abstract: An example of the Julia–Lythgoe attachment of the vitamin D side chain to a solid-phase linked Inhoffen–Lythgoe diol derived CD-ring fragment is reported.

Keywords: Julia–Lythgoe olefination; solid-phase synthesis; vitamin D.

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Cite This Article

MDPI and ACS Style

D'herde, J.N.; De Clercq, P.J. Application of the Solid-Phase Julia–Lythgoe Olefination in Vitamin D Side-Chain Construction. Molecules 2006, 11, 655-660.

AMA Style

D'herde JN, De Clercq PJ. Application of the Solid-Phase Julia–Lythgoe Olefination in Vitamin D Side-Chain Construction. Molecules. 2006; 11(8):655-660.

Chicago/Turabian Style

D'herde, Jo N.; De Clercq, Pierre J. 2006. "Application of the Solid-Phase Julia–Lythgoe Olefination in Vitamin D Side-Chain Construction." Molecules 11, no. 8: 655-660.

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