Next Article in Journal
Synthesis and Structure of a Sodium Complex of an Aromatic β-Diketone and Pyrazolylpyridine
Previous Article in Journal
Electrocoagulation of Quinone Pigments
Molecules 2006, 11(7), 523-527; doi:10.3390/11070523
Communication

[Hydroxy(tosyloxy)iodo]benzene Mediated α-Azidation of Ketones

* , ,  and
Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana, India
* Author to whom correspondence should be addressed.
Received: 20 August 2005 / Revised: 10 March 2006 / Accepted: 12 March 2006 / Published: 14 July 2006
View Full-Text   |   Download PDF [62 KB, uploaded 18 June 2014]   |  

Abstract

Reaction of various ketones with [hydroxy(tosyloxy)iodo]benzene (HTIB) followed by treatment of the α-tosyloxy ketones thus generated in situ with NaN3 offers a one-pot procedure for the synthesis of α-azido ketones. The HTIB used in this conversion may also be generated in situ by using iodosobenzene in combination with p-toluene- sulphonic acid.
Keywords: Hypervalent iodine; α-azido ketones; [hydroxy(tosyloxy)iodo]benzene; iodosobenzene. Hypervalent iodine; α-azido ketones; [hydroxy(tosyloxy)iodo]benzene; iodosobenzene.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
SciFeed

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Prakash, O.; Pannu, K.; Prakash, R.; Batra, A. [Hydroxy(tosyloxy)iodo]benzene Mediated α-Azidation of Ketones. Molecules 2006, 11, 523-527.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert