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Molecules 2006, 11(6), 383-392; doi:10.3390/11060383
Article

Synthesis and Antifungal Bioactivities of 3-Alkylquinazolin- 4-one Derivatives

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Received: 26 April 2006; Accepted: 12 June 2006 / Published: 12 June 2006
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Abstract: A simple, efficient, and general method has been developed for the synthesis ofvarious 3-alkylquinazolin-4-one derivatives from quinazolin-4-one treated with alkylbromides under phase transfer catalysis condition. The structures of the compounds werecharacterized by elemental analysis, IR, 1H-NMR and 13C-NMR spectra. Title compound6-bromo-3-propylquinazolin-4-one (3h) was found to possess good antifungal activity.
Keywords: Quinazolinone; Phase Transfer Catalyst; synthesis; antifungal activity Quinazolinone; Phase Transfer Catalyst; synthesis; antifungal activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Ouyang, G.; Zhang, P.; Xu, G.; Song, B.; Yang, S.; Jin, L.; Xue, W.; Hu, D.; Lu, P.; Chen, Z. Synthesis and Antifungal Bioactivities of 3-Alkylquinazolin- 4-one Derivatives. Molecules 2006, 11, 383-392.

AMA Style

Ouyang G, Zhang P, Xu G, Song B, Yang S, Jin L, Xue W, Hu D, Lu P, Chen Z. Synthesis and Antifungal Bioactivities of 3-Alkylquinazolin- 4-one Derivatives. Molecules. 2006; 11(6):383-392.

Chicago/Turabian Style

Ouyang, Guiping; Zhang, Peiquan; Xu, Gangfang; Song, Baoan; Yang, Song; Jin, Linhong; Xue, Wei; Hu, Deyu; Lu, Ping; Chen, Zhuo. 2006. "Synthesis and Antifungal Bioactivities of 3-Alkylquinazolin- 4-one Derivatives." Molecules 11, no. 6: 383-392.


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