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Molecules 2006, 11(5), 365-369; doi:10.3390/11050365

Selective Enzymatic Reduction of Aldehydes

1,* , 1, 1 and 2
1 Dipartimento di Chimica Organica e Industriale, Università degli Studi di Milano, via Venezian 21, 20133 Milano, Italy 2 Dipartimento di Scienze dell’Ambiente e del Territorio, Università di Milano-Bicocca, della Scienza 1, 20126 Milano, Italy
* Author to whom correspondence should be addressed.
Received: 22 February 2006 / Accepted: 7 March 2006 / Published: 12 May 2006
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Highly selective enzymatic reductions of aldehydes to the corresponding alcohols was performed using an E. coli JM109 whole cell biocatalyst. A selective enzymatic method for the reduction of aldehydes could provide an eco-compatible alternative to chemical methods. The simplicity, fairly wide scope and the very high observed chemoselectivity of this approach are its most unique features.
Keywords: Enzyme reaction; aldehydes; reduction; chemoselectivity. Enzyme reaction; aldehydes; reduction; chemoselectivity.
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Sello, G.; Orsini, F.; Bernasconi, S.; Di Gennaro, P. Selective Enzymatic Reduction of Aldehydes. Molecules 2006, 11, 365-369.

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