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Molecules 2006, 11(4), 272-278; doi:10.3390/11040272
Article

Microwave Assisted Synthesis of N-Arylheterocyclic Substituted-4-aminoquinazoline Derivatives

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Center for Research and Development of Fine Chemicals, Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guiyang, 550025, P. R. China
* Author to whom correspondence should be addressed.
Received: 16 January 2006 / Revised: 25 March 2006 / Accepted: 7 April 2006 / Published: 10 April 2006
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Abstract

A simple, efficient, and general method has been developed for the synthesis of various N-aryl heterocylic substituted-4-aminoquinazoline compounds from 4-chloro- quinazoline and aryl heterocyclic amines under microwave irradiation using 2-propanol as solvent. The advantages of the use of microwave irradiation in relation to the classical method were demonstrated.
Keywords: 4-Aminoquinazoline; Heterocyclic moiety; Microwave irradiation. 4-Aminoquinazoline; Heterocyclic moiety; Microwave irradiation.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Liu, G.; Yang, S.; Song, B.; Xue, W.; Hu, D.; Jin, L.; Lu, P. Microwave Assisted Synthesis of N-Arylheterocyclic Substituted-4-aminoquinazoline Derivatives. Molecules 2006, 11, 272-278.

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