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Molecules 2006, 11(4), 272-278; doi:10.3390/11040272

Microwave Assisted Synthesis of N-Arylheterocyclic Substituted-4-aminoquinazoline Derivatives

* ,
Center for Research and Development of Fine Chemicals, Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guiyang, 550025, P. R. China
* Author to whom correspondence should be addressed.
Received: 16 January 2006 / Revised: 25 March 2006 / Accepted: 7 April 2006 / Published: 10 April 2006
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A simple, efficient, and general method has been developed for the synthesis of various N-aryl heterocylic substituted-4-aminoquinazoline compounds from 4-chloro- quinazoline and aryl heterocyclic amines under microwave irradiation using 2-propanol as solvent. The advantages of the use of microwave irradiation in relation to the classical method were demonstrated.
Keywords: 4-Aminoquinazoline; Heterocyclic moiety; Microwave irradiation. 4-Aminoquinazoline; Heterocyclic moiety; Microwave irradiation.
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Liu, G.; Yang, S.; Song, B.; Xue, W.; Hu, D.; Jin, L.; Lu, P. Microwave Assisted Synthesis of N-Arylheterocyclic Substituted-4-aminoquinazoline Derivatives. Molecules 2006, 11, 272-278.

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