Molecules 2006, 11(10), 758-767; doi:10.3390/11100758
Article

Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea

George A. Kraus 1,* email, Jaehoon Bae 1 , Lankun Wu 2  and Eve Wurtele 2
1 Iowa State University Department of Chemistry, Ames, IA 50011, USA 2 Iowa State University Department of Genetics, Development and Cell Biology, Ames, IA 50011, USA
* Author to whom correspondence should be addressed.
Received: 2 September 2006; in revised form: 10 October 2006 / Accepted: 16 October 2006 / Published: 18 October 2006
PDF Full-text Download PDF Full-Text [200 KB, uploaded 20 June 2008 16:50 CEST]
Abstract: The synthesis of the alkamides 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (1) and 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (5) was accomplished by organometallic coupling followed by introduction of the doubly unsaturated amide moiety. The distribution of these two amides in accessions of the nine species of Echinacea was determined.
Keywords: Echinacea; alkamides; synthesis.

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Kraus, G.A.; Bae, J.; Wu, L.; Wurtele, E. Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea. Molecules 2006, 11, 758-767.

AMA Style

Kraus GA, Bae J, Wu L, Wurtele E. Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea. Molecules. 2006; 11(10):758-767.

Chicago/Turabian Style

Kraus, George A.; Bae, Jaehoon; Wu, Lankun; Wurtele, Eve. 2006. "Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea." Molecules 11, no. 10: 758-767.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert