Next Article in Journal
Synthesis of New Unsymmetrical 4,5-Dihydroxy-2-imidazolidinones. Dynamic NMR Spectroscopic Study of the Prototropic Tautomerism in 1-(2-Benzimidazolyl)-3-phenyl-4,5-dihydroxy-2-imidazolidinone
Previous Article in Journal
A Simple and Cost Effective Synthesis of 3,11-Dimethylnonacosan-2-one, A Female Sex Pheromone of the German Cockroach
Article Menu

Export Article

Open AccessArticle
Molecules 2006, 11(10), 758-767; doi:10.3390/11100758

Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea

Iowa State University Department of Chemistry, Ames, IA 50011, USA
Iowa State University Department of Genetics, Development and Cell Biology, Ames, IA 50011, USA
Author to whom correspondence should be addressed.
Received: 2 September 2006 / Revised: 10 October 2006 / Accepted: 16 October 2006 / Published: 18 October 2006
View Full-Text   |   Download PDF [200 KB, uploaded 18 June 2014]   |  


The synthesis of the alkamides 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (1) and 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (5) was accomplished by organometallic coupling followed by introduction of the doubly unsaturated amide moiety. The distribution of these two amides in accessions of the nine species of Echinacea was determined.
Keywords: Echinacea; alkamides; synthesis. Echinacea; alkamides; synthesis.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Kraus, G.A.; Bae, J.; Wu, L.; Wurtele, E. Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea. Molecules 2006, 11, 758-767.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top