An Aromatic Iodination Method, with Iodic Acid Used as the Only Iodinating Reagent†

doi:10.3390/10020394

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Molecules 2005, 10(2), 394-400; doi:10.3390/10020394

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An Aromatic Iodination Method, with Iodic Acid Used as the Only Iodinating Reagent†

Barbara Krassowska-Swiebocka, Grazyna Prokopienko and Lech Skulski *

Chair and Laboratory of Organic Chemistry, Faculty of Pharmacy, Medical University, Banacha 1, PL02-097 Warsaw, Poland

* Author to whom correspondence should be addressed.

Received: 8 November 2004; in revised form: 28 January 2005 / Accepted: 29 January 2005 / Published: 28 February 2005

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Abstract: Benzene, halobenzenes, and a number of more or less deactivated arenes,including nitrobenzene, readily reacted in anhydrous HIO₃/AcOH/Ac₂o/conc. H₂SO₄mixtures to probably give ArIO₂ intermediates or other hypervalent species (notisolated). The final reaction mixtures were poured into excess aq. Na₂SO₃ solution (areductant) to give the purified iodinated products in 39-83% yields.

Keywords: Arenes; iodoarenes; aromatic iodination; iodic acid as reactant and iodinating agent

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MDPI and ACS Style

Krassowska-Swiebocka, B.; Prokopienko, G.; Skulski, L. An Aromatic Iodination Method, with Iodic Acid Used as the Only Iodinating Reagent†. Molecules 2005, 10, 394-400.

AMA Style

Krassowska-Swiebocka B., Prokopienko G., Skulski L. An Aromatic Iodination Method, with Iodic Acid Used as the Only Iodinating Reagent†. Molecules. 2005; 10(2):394-400.

Chicago/Turabian Style

Krassowska-Swiebocka, Barbara; Prokopienko, Grazyna; Skulski, Lech. 2005. "An Aromatic Iodination Method, with Iodic Acid Used as the Only Iodinating Reagent†." Molecules 10, no. 2: 394-400.

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